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Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity
(Elsevier B.V., 2007-12-01)
BjussuMP-II is an acidic low molecular weight metalloprotease (Mr similar to 24,000 and pI similar to 6.5), isolated from Bothrops jararacussu snake venom. The chromatographic profile in RP-HPLC and its N-terminal sequence ...
Molecular characterization of an acidic phospholipase A(2) from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region
(Springer, 2011-10-01)
This paper describes a biochemical and pharmacological characterization of BpirPLA(2)-I, the first acidic Asp49-PLA(2) isolated from Bothrops pirajai. BpirPLA(2)-I caused hypotension in vivo, presented phospholipolytic ...
Anti-platelet activity of infusion of Tithonia diversifolia's leaves
(2012-08-20)
Tithonia diversifolia, also known as Mexican arnica, has been used in traditional medicine to treat inflammatory refractory with absence of citotoxicity. The possible health risks associated with the consumption of ingestion ...
Role of ticlopidine on adriamycin-induced nephropathy
(1999-10-11)
The effect of ticlopidine on rats with adriamycin nephropathy was observed during 26 weeks. In the ticlopidine-treated nephrotic animals (TNG), proteinuria was less than in the untreated nephrotic animals (NG), but this ...
Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease
(Wiley-Blackwell, 2015)
Influence of Antiplatelet Drugs in the Pathogenesis of Experimental Periodontitis and Periodontal Repair in Rats
(Amer Acad Periodontology, 2011-05-01)
Background: Platelets contain an array of biologic mediators that can modulate inflammation and repair processes including proinflammatory mediators and growth factors. Previous studies have shown that periodontitis and ...
Prognostic Implications of Dual Platelet Reactivity Testing in Acute Coronary Syndrome
(Schattauer Gmbh-Verlag Medizin Naturwissenschaften, 2018)
Studies on platelet reactivity (PR) testing commonly test PR only after percutaneous coronary intervention (PCI) has been performed. There are few data on pre-and post-PCI testing. Data on simultaneous testing of aspirin ...