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Identification of cytoplasmic soluble antigens related to the major surface antigens of Leishmania braziliensis braziliensis and L. donovani chagasi
(Parasitol Res., 1990)
Abstract. This study describes the identification of aqueous-soluble antigens in Leishmania promastigotes immunologically and biochemically closely related to the major surface antigen. Proteins from surface-iodinated L. ...
Identification of cytoplasmic soluble antigens related to the major surface antigens of Leishmania braziliensis braziliensis and L. donovani chagasi
(Parasitol Res., 1990)
Abstract.
This study describes the identification of aqueous-soluble antigens in Leishmania promastigotes immunologically and biochemically closely related to the major surface antigen. Proteins from surface-iodinated ...
Antigen presentation unfolded: identifying convergence points between the UPR and antigen presentation pathways
(Elsevier, 2018-06)
The unfolded protein response (UPR) is an adaptive response meant to restore endoplasmic reticulum homeostasis in conditions of ER stress that subvert the folding capacity of the cell. Over the past few years, it has become ...
Bovine derived in vitro cultures generate heterogeneous populations of antigen presenting cells
(Frontiers Media, 2019)
Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses. Many of the biological functions ...
MHC I presentation of Toxoplasma gondii immunodominant antigen does not require Sec22b and is regulated by antigen orientation at the vacuole membrane
(Wiley VCH Verlag, 2017-07)
The intracellular Toxoplasma gondii parasite replicates within a parasitophorous vacuole (PV). T. gondii secretes proteins that remain soluble in the PV space, are inserted into PV membranes or are exported beyond the PV ...
Takayasu Arteritis: Recent Developments
(Springer, 2019)
Purpose of Review: Takayasu arteritis (TA) is a granulomatous inflammatory disorder that affects large vessels, especially aorta and its proximal branches. Its diagnosis can be extremely challenging due to the non-specificity ...