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Age at menopause in Latin America
(2006)
OBJECTIVE: To assess the age at menopause (AM) in Latin America urban areas. DESIGN: A total of 17,150 healthy women, aged 40 to 59 years, accompanying patients to healthcare centers in 47 cities of 15 Latin American ...
Prepubertal Adiposity, Vitamin D Status, and Insulin Resistance
(Amer Acad Pediatrics, 2016)
OBJECTIVE: To evaluate the following from prepuberty to the puberty-onset: (1) changes in serum 25-hydroxyvitamin-D (25[OH]D), adiposity, and insulin resistance (IR); (2) the effect of prepubertal adiposity on serum 25(OH)D ...
Impact of being born small for gestational age on onset and progression of puberty
(BAILLIERE TINDALL, 2008-06)
Children born small for gestational age (SGA) are at higher risk for perinatal morbidity, mortality and chronic diseases in later life. There is increasing evidence for a link between prenatal growth and pubertal development, ...
La pubertad en niños chilenos muestra un adelantamiento en el inicio del crecimiento testicular
(Soc. Médica Santiago, 2015)
Background: A secular trend towards a younger age of puberty onset has been reported in Chilean girls. Aim: To evaluate the age of onset of puberty and prevalence of early puberty in Chilean boys. Material and Methods: A ...
Revealing the clinical phenotype of atypical neuronal ceroid lipofuscinosis type 2 disease: Insights from the largest cohort in the world
(Wiley, 2020)
Aim: Neuronal ceroid lipofuscinosis type 2 (CLN2) disease is an autosomal recessive inherited neurodegenerative lysosomal storage disorder
caused by deficient tripeptidyl peptidase 1 (TPP1) enzyme, leading to progressive ...
Obesity and impairment of pancreatic beta-cellfunction in early adulthood, independent of obesity age of onset: The Santiago Longitudinal Study
(Wiley, 2020)
Aim: We investigated the relation of time of onset and length of obesity with biomarkers of beta-cell function in early adulthood in an infancy cohort.
Material and methods: In 1039 23-year-olds, body-mass index (BMI) ...
Age and season affect chemical discrimination of Liolaemus bellii own space
(2003)
We explored chemical discrimination of own vs. novel space by different age classes (neonates, juveniles, and adults) of the lizard Liolaemus bellii, during pre- and post-hibernation seasons. We recorded the number of ...
Type 1 diabetes mellitus incidence in Santiago, Chile. Analysis by counties in the period 2000-2004 Incidencia de diabetes mellitus tipo 1 en Santiago de Chile: Análisis por comunas de la Region Metropolitana en el período 2000-2004
(2006)
Background: There are great geographical differences in the incidence of type I diabetes mellitus. Aim: To determine the incidence rate of type 1 diabetes mellitus (DM1) in the Metropolitan Region of Santiago, Chile from ...
Breast bud detection: a validation study in the Chilean Growth Obesity Cohort Study
(BioMed Central, 2014)
Background: Early puberty onset has been related to future chronic disease; however breast bud assessment in
large scale population studies is difficult because it requires trained personnel. Thus our aim is to assess the ...
A polygenic risk score suggests shared genetic architecture of voice break with early markers of pubertal onset in boys
(Endocrine Society, 2020)
Context: Voice break, as a landmark of advanced male puberty in genome-wide association studies (GWAS), has revealed that pubertal timing is a highly polygenic trait. Although voice break is easily recorded in large cohorts, ...