Buscar
Mostrando ítems 1-10 de 184
Organic Acids without a Carboxylic Acid Functional Group
(Journal of Chemical Education 77(7):910-915. July 2000, 2000-07)
This paper presents several organic molecules that have been labeled as acids but do not contain a carboxylic acid functional group. The rationale for the nomenclature and appropriate explanations for the apparent acidity ...
Autocatalytic acylation of phospholipase-like myotoxins
(1995-04)
Several snake venoms contain a phospholipase A2 in which position 49 in the active site is occupied by a lysine or a serine instead of the aspartate residue normally found. Although these proteins do not bind Ca2+ and are ...
Characterization of alpha-neurotoxin and phospholipase A2 activities from Micrurus venoms. Determination of the amino acid sequence and receptor-binding ability of the major alpha-neurotoxin from Micrurus nigrocinctus nigrocinctus
(1996)
New World elapids are coral snakes that belong to the genus Micrurus, and for which the venom biochemistry is mostly unknown. Analysis has been difficult because the coral snakes produce small quantities of venom. Clinical ...
An acidic phospholipase A2 with antibacterial activity from Porthidium nasutum snake venom
(2012-04)
Snake venoms are complex mixtures of proteins among which both basic and acidic phospholipases A2
(PLA2s) can be found. Basic PLA2s are usually responsible for major toxic effects induced by snake venoms,
while acidic ...
The amino acid sequence of a myotoxic phospholipase from the venom of Bothrops asper
(1990)
A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation. It is distinct ...
Stability of equine IgG antivenoms obtained by caprylic acid precipitation: Towards a liquid formulation stable at tropical room temperature
(2009-05)
Liquid formulations of antivenom require a cold chain for their distribution and storage, especially in tropical countries characterized by high temperature and humidity (climatic zone IV). Since cold chain is often deficient ...
Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom
(2012-12-01)
The aim of this study was the isolation of the LAAO from Lachesis muta venom (LmLAAO) and its biochemical, functional and structural characterization. Two different purification protocols were developed and both provided ...
Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa
(2005-06)
A polyspecific Pan-African antivenom has been produced from the plasma of horses immunized with a mixture of the venoms of Echis ocellatus, Bitis arietans and Naja nigricollis, the three most medically important snakes in ...
Influence of Orally Administered Antibiotics on Faecal pH and Volatile Fatty Acid Concentrations on Infants and Young Children
(1990)
Faecal specimens were collected from infants and children with common infections who presented to the Paediatrics Outpatient Department of the National Children's Hospital, San Jose, Costa Rica or to the Paediatrics Clinic, ...
Amino acid sequence of a myotoxic Lys49-phospholipase A2 homologue from the venom of Cerrophidion (Bothrops) godmani
(1998-05-19)
The complete amino acid sequence of myotoxin II (godMT-II), a myotoxic phospholipase A2 (PLA2) homologue from the venom of the Central American crotaline snake Cerrophidion (Bothrops) godmani, was determined by direct ...