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3 SUBTYPES OF ALPHA-BUNGAROTOXIN SENSITIVE NICOTINIC ACETYLCHOLINE-RECEPTORS ARE EXPRESSED IN CHICK RETINA
(Soc Neuroscience, 1993-02-01)
A recent report described the isolation of cDNA clones encoding alpha7 and alpha8 subunits of alpha-bungarotoxin-sensitive nicotinic ACh receptors (alphaBgtAChRs) from chick brain and demonstrated that they were related ...
Determination of the stoichiometry between alpha- and gamma 1 subunits of the BK channel using LRET
(Cell Press, 2018)
Two families of accessory proteins, beta and gamma, modulate BK channel gating and pharmacology. Notably, in the absence of internal Ca2+, the gamma 1 subunit promotes a large shift of the BK conductance-voltage curve to ...
Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel
(ROCKEFELLER UNIV PRESS, 2006-02)
High conductance, calcium- and voltage-activated potassium (BK, MaxiK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory ...
Heterotrimeric G protein alpha subunit controls growth, stress response, extracellular protease activity, and cyclopiazonic acid production in Penicillium camemberti
(Elsevier, 2017)
The fungus Penicillium camemberti is widely used in the ripening of various bloomy-rind cheeses. Several properties of P. camemberti are important in cheese ripening, including conidiation, growth and enzyme production, ...
The alpha(1)-beta-subunit interaction that modulates calcium channel activity is reversible and requires a competent alpha-interaction domain
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2006)
Differential effects of beta 1 and beta 2 subunits on BK channel activity
(ROCKEFELLER UNIV PRESS, 2005-04)
High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice
(BioMed Central, 2019-06)
Go is a member of the pertussis toxin-sensitive Gi/o family. Despite its abundance in the central nervous system, the precise role of Go remains largely unknown compared to other G proteins. In the present study, we explored ...
Monoclonal-antibodies specific for the free alpha-subunit of glycoprotein hormones and their use in the development of a sensitive immunofluorometric assay
(Assoc Bras Divulg Cientifica, 1995-06-01)
Glycoprotein hormone free alpha subunit has been used as a marker for some pituitary tumors and to study the reactivity of glycoprotein hormone-producing cells under different circumstances. We describe a highly sensitive ...
CK2 alpha/CK1 alpha chimeras are sensitive to regulation by the CK2 beta subunit
(Springer, 2008)
The effect of CK2 beta on the activity of CK2 alpha and other protein kinases that can bind this regulatory subunit is not fully understood. In an attempt to improve our understanding of this effect, chimeras of CK2 alpha ...
Regulation of PKD1-mediated Golgi to cell surface trafficking by Gαq subunits
(Wiley, 2013-12)
Background Information: Heterotrimeric GTP-binding proteins play a key role in cell trafficking regulation. Above all, specific Gβγ subunits have been shown to be a major component of a signal transduction pathway, which ...