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Níveis de ADAM10 no líquido cefalorraquidiano e soro de indivíduos com doença de Alzheimer
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Gerontologia - PPGGeroCâmpus São Carlos, 2018-11-12)
Researchers have pointed out that the identification of ADAM10 as a biomarker can be an important tool to aid in the clinical diagnosis of AD. The proposal of ADAM10 as a biomarker occurs because it is involved in different ...
Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2
(2018)
Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
Involvement of TACE/ADAM17 and ADAM10 in etoposide-induced apoptosis of germ cells in rat spermatogenesis
(WILEY-BLACKWELL, 2012-02)
Germ cell apoptosis is important to regulate sperm production in the mammalian testis, but the molecular mechanisms underlying apoptosis are still poorly understood. We have recently shown that in vitro, etoposide induces ...
Avaliação do perfil de expressão de ADAM23 durante o processo de diferenciação neuronal
(Universidade Estadual de Ponta GrossaBrasilSetor de Ciências Biológicas e da SaúdePrograma de Pós-Graduação em Ciências BiomédicasUEPG, 2019)
Presence, processing, and localization of mouse ADAM15 during sperm maturation and the role of its disintegrin domain during sperm egg binding
(2008)
Successful fertilization requires gametes to complete several stages, beginning with maturation and transport along the male and femalereproductive tracts and ending with the interaction between the sperm and the egg. This ...
ADAM10 como biomarcador para a doença de Alzheimer
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Enfermagem - PPGEnf, 2012-02-24)
Alzheimer's disease (AD) is the most common cause of dementia in people over 65 years. Platelet studies with ADAM10 have shown to decrease its expression in AD patients. The association between cognitive testing and molecular ...
Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2
(Wiley-Liss Inc., 2018)
Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
A Desintegrina e Metaloproteinase 10 (ADAM10) como biomarcadora para a doença de Alzheimer: uma revisão sistemática
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Gerontologia - PPGGeroCâmpus São Carlos, 2022-08-08)
Introduction: Studies have shown that Disintegrin and Metalloproteinase 10 (ADAM10) is the
main α-secretase in the non-amyloidogenic cleavage of amyloid precursor protein (APP). ADAM10
prevents the production of β-amyloid ...