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Protective effects of lemongrass (Cymbopogon citratus STAPF) essential oil on DNA damage and carcinogenesis in female Balb/C mice
(Wiley-Blackwell, 2011-08-01)
This study investigated the protective effect of oral treatment with lemongrass (Cymbopogon citratus STAPF) essential oil (LGEO) on leukocyte DNA damage induced by N-methyl-N-nitrosurea (MNU). Also, the anticarcinogenic ...
Lymphoproliferative response and T lymphocyte subsets in a medium-term multi-organ bioassay for carcinogenesis in Wistar rats
(Elsevier B.V., 2000-06-30)
The lymphoproliferative response and T lymphocyte subsets were evaluated at different stages of carcinogenesis in male Wistar, rats sequentially initiated with N-diethylnitrosamine (DEN), N-butyl-N-4(hydroxybutyl)nitrosamine ...
Enhancement of colon carcinogenesis by the combination of indole-3 carbinol and synbiotics in hemin-fed rats
(2018-02-01)
The risk of developing colorectal cancer (CRC) could be associated with red and processed meat intake. Experimental data supports that hemin iron, found abundantly in red meat, promotes CRC in mice and rats, while indole-3 ...
Screening for In Vitro and In Vivo Antitumor Activities of the Mushroom Agaricus Blazei
(Lawrence Erlbaum Assoc Inc-taylor & Francis, 2009-01-01)
We have investigated the in vitro antitumor activity of the mushroom Agaricus blazei Murill on human cancer cell lines as well as its potential anticancer activity in a model of rat colon carcinogenesis. The in vitro ...
Comparison of the effects of aqueous extract of Sida cordifolia L. and 5-fluorouracil in colon carcinogenesis induced by 1,2- dimethylhydrazine on Wistar rats
(Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde, 2022)
Early molecular events associated with liver and colon sub-acute responses to 1,2-dimethylhydrazine: Potential implications on preneoplastic and neoplastic lesion development
(2020-09-01)
This study unveiled the early cellular and molecular events induced by 1,2-dimethylhydrazine (DMH) in the colon and liver and their implications on pre- and neoplastic lesion burden in a late timepoint. Male Wistar rats ...
Capsaicin reduces genotoxicity, colonic cell proliferation and preneoplastic lesions induced by 1,2-dimethylhydrazine in rats
(2018-01-01)
Capsaicin (8-Methyl-N-vanillyl-(trans)-6-nonenamide) is the major pungent ingredient found in chili peppers consumed worldwide. Most reports on capsaicin potential carcinogenicity have yielded inconsistent findings. Some ...
Disminución del desarrollo de cáncer experimental del colon en ratas alimentadas con leche de búfala
(Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias., 2012)
La leche bovina contiene elementos potencialmente capaces de inhibir la carcinogénesis; a su vez, la leche bubalina tiene un alto valor debido a su mayor concentración de sólidos totales, grasa, proteína y lactosa. El ...
Comparison of the effects of aqueous extract of Sida cordifolia L. and 5-fluorouracil in colon carcinogenesis induced by 1,2- dimethylhydrazine on Wistar rats
(Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde, 2022)