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Dehydroepiandrosterone (DHEA) modulates GHRH, somatostatin and angiotensin II action at the pituitary level
(BioScientifica, 2005-04-01)
In view of the present controversy related to the potential beneficial effects of clinical dehydroepiandrosterone (DHEA) treatments, and considering our own previous results that reveal an influence of this steroid in ...
Opposite effects of dihydrotestosterone and estradiol on apoptosis in the anterior pituitary gland from male rats
(Springer, 2016-03)
Hormones locally synthesized in the anterior pituitary gland are involved in regulation of pituitary cell renewal. In the pituitary, testosterone (T) may exert its actions per se or by conversion to dihydrotestosterone ...
Upregulation of Angiotensin II type 2-receptor expression in estrogen-induced pituitary hyperplasia
(American Physiological Society, 2004-01)
Recent evidence shows that reexpression and upregulation of angiotensin II (ANG II) type 2 (AT2) receptor in adult tissues occur during pathological conditions such as tissue hyperplasia, inflammation, and remodeling. In ...
Role of nitric oxide in the metabolism of arachidonic acid in the rat anterior pituitary gland
(Elsevier Ireland, 2001-02)
Nitric oxide (NO) affects cyclooxygenase (COX) and lipooxygenase (LOX) activities in several tissues. The aim of this study was to investigate the effect of NO on the AA metabolism in the anterior pituitary. LOX and COX ...