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Mostrando ítems 4451-4460 de 9630
The early molecular events leading to COFILIN phosphorylation during mouse sperm capacitation are essential for acrosomal exocytosis
(American Society for Biochemistry and Molecular Biology, 2022-06)
The actin cytoskeleton reorganization during sperm capacitation is essential for the occurrence of acrosomal exocytosis (AR) in several mammalian species. Here, we demonstrate that in mouse sperm, within the first minutes ...
MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset
(Public Library of Science, 2017-11-02)
Macrophages contribute in the initiation and progression of insulitis during type 1 diabetes (T1D). However, the mechanisms governing their recruitment into the islets as well as the manner of retention and activation are ...
Effect of storage temperature on dormancy release of sunflower (Helianthus annuus) achenes
(Cambridge University Press, 2018-06)
Published information regarding the effect of storage temperature on dormancy alleviation of sunflower achenes is contradictory and ambiguous. In the present study we explored the effect of temperature during dry storage ...
Virucidal, antiviral and immunomodulatory activities of β-escin and Aesculus hippocastanum extract
(Wiley, 2018-11)
Objectives: β-Escin, one of the constituents of Aesculus hippocastanum L. (Hippocastanaceae) seed extract (AH), inhibits NF-κB activation, which plays an important role in HSV-1 replication. The aim was to examine the ...
Down-regulation of catalase activity contributes to senescence induction in wheat leaves exposed to shading stress
(Springer, 2015-01)
In shaded wheat (Triticum aestivum L.) leaves, the suppression of blue radiation (BR) triggers senescence. This phenomenon is correlated to an increase in oxidative stress symptoms and a decrease of catalase (CAT) activity, ...
Hexachlorobenzene Induces Deregulation of Cellular Growth in Rat Liver
(Elsevier Ireland, 2011-10)
Hexachlorobenzene (HCB) is an organochlorine pesticide widely distributed in the biosphere. The aim of the present study was to investigate the effect of HCB on the homeostasis of liver cell growth, analyzing parameters ...
Behavioral sensitization and cellular responses to psychostimulants are reduced in D2R knockout mice
(Wiley Blackwell Publishing, Inc, 2019-12)
Repeated cocaine exposure causes long-lasting neuroadaptations that involve alterations in cellular signaling and gene expression mediated by dopamine in different brain regions, such as the striatum. Previous studies have ...
Patents on plant transcription factors
(Bentham Science Publishers B.V., 2008-12)
Transcription factors are clue elements in the regulation of signal transduction pathways in living organisms. These proteins are able to recognize and bind specific sequences in the promoter regions of their targets and ...
Transcriptome profile in the skeletal muscle of cattle progeny as a function of maternal protein supplementation during mid-gestation
(2022)
This study aimed to evaluate the differentially expressed genes (DEG), their biological functions, and the main predictor genes in skeletal muscle of the offspring resulting from dams supplemented or not with protein during ...
A apoptose induzida pelo anti-inflamatório não esteróide salicilato de sódio requer a participação da proteína cinase gcn2 e o envolvimento de vias do estresse do retículo endoplasmático
(Universidade Federal de Minas GeraisUFMG, 2011-12-20)
Salicylates are non-steroidal anti-inflammatory drugs with the well-known ability to inhibit cyclooxygenase activity, the key enzyme in prostaglandin biosynthesis. The salicylates also induce the phosphorylation of the ...