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Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: Involvement of the NO/cGMP/PKG/KATP signaling pathway
(Elsevier Science BvAmsterdamHolanda, 2010)
Geopropolis from Melipona scutellaris decreases the mechanical inflammatory hypernociception by inhibiting the production of IL-1 beta and TNF-alpha
(ELSEVIER IRELAND LTDCLARE, 2012)
Ethnopharmacological relevance: The pharmacological activity of geopropolis collected by stingless bees (important and threatened pollinators), a product widely used in folk medicine by several communities in Brazil, ...
The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its Na(v)1.8 sodium channel functional regulation in the primary sensory neuron
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
In the present study, the participation of the Na(v)1.8 sodium channel was investigated in the development of the peripheral pro-nociceptive state induced by daily intraplantar injections of PGE(2) in rats and its regulation ...
The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its NaV1.8 sodium channel functional regulation in the primary sensory neuron
(2009)
In the present study, the participation of the NaV1.8 sodium channel was investigated in the development of the peripheral pro-nociceptive state induced by daily intraplantar injections of PGE2 in rats and its regulation ...
Anti-hyperalgesic And Anti-inflammatory Activity Of Alternanthera Maritima Extract And 2 ''-o-alpha-l-rhamnopyranosylvitexin In Mice
(SPRINGER/PLENUM PUBLISHERSNEW YORK, 2015)
Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway
(Hindawi Publishing CorporationNew YorkEUA, 2013)
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout
(WILEY-BLACKWELLMALDEN, 2012)
Objective Deposition of monosodium urate monohydrate (MSU) crystals in the joints promotes an intense inflammatory response and joint dysfunction. This study evaluated the role of the NLRP3 inflammasome and 5-lipoxygenase ...
Investigação da atividade Farmacológica de espécies de Piper que ocorrem no Cerrado
(Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde., 2017)
Protective effect of an extract from Ascaris suum in experimental arthritis models
(AMER SOC MICROBIOLOGY, 2008)
We investigated the effect of an extract from a helminth (Ascaris suum) in zymosan-induced arthritis (ZYA) or collagen-induced arthritis (CIA). Rats and mice, respectively, received 1 mg and 0.1 mg zymosan intra-articularly ...
Estudo da resposta inflamatória na artrite induzida por antígeno e o papel de mediadores endógenos na sua resolução: importância das espécies reativas de oxigênio
(Universidade Federal de Minas GeraisUFMG, 2013-02-18)
During inflammatory response there an important accumulation (arrival and permanence at inflamed site) of leukocytes, production of inflammatory mediators and, conse quently, loss of function of involved organ. Neutrophils ...