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Canine leishmaniasis: Genome-wide analysis and antibody response to Lutzomyia longipalpis saliva
(Public Library Science, 2018-05-09)
The anti-inflammatory properties of sand fly saliva favor the establishment of the Leishmania infantum infection. In contrast, an antibody response against Lutzomyia longipalpis saliva is often associated with a protective ...
Estudios citogenéticos y moleculares en una población sorda institucionalizada con síndrome de waardenburg en colombia
(Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de Biología, 2001)
El Síndrome de Waardenburg (WS) es un desorden autosómico dominante caracterizado por sordera neurosensorial y anormalidades pigmentarias en la piel y faneras. Es clínica y genéticamente heterogéneo y ha sido dividido en ...
A Situação do Câncer de Pele em Missal, PR: Investigação de Mutações no Gene CDKN2A Relacionado ao Melanoma na População
(Christopher Lee, 2020-11-01)
Durante as últimas décadas, o município de Missal, localizado no oeste paranaense, apresentou um grande aumento na incidência de câncer na população e dados de 2016 demonstraram que o câncer é a segunda maior causa de óbito ...
Genome Sequence Analysis Reveals Selection Signatures in Endangered Trypanotolerant West African Muturu Cattle
(Frontiers Media Sa, 2019-06-04)
Like most West African Bos taurus, the shorthorn Muturu is under threat of replacement or crossbreeding with zebu. Their populations are now reduced to a few hundred breeding individuals and they are considered endangered. ...
Uncovering Signals of Positive Selection in Peruvian Populations from Three Ecological Regions
(Oxford Academic, 2022-07-21)
Peru hosts extremely diverse ecosystems which can be broadly classified into the following three major ecoregions: the Pacific desert coast, the Andean highlands, and the Amazon rainforest. Since its initial peopling ...
Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers
(Nature Publishing Group, 2016-11)
Nuclear 3'-end-polyadenylation is essential for the transport, stability and translation of virtually all eukaryotic mRNAs. Poly(A) tail extension can also occur in the cytoplasm, but the transcripts involved are incompletely ...