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Role of muscarinic acetylcholine receptors in Breast Cancer. Design of metronomic chemotherapy.
(Bentham Science Publishers, 2018-12)
Background: muscarinic acetylcholine receptors (mAChRs) have attracted interest as targets for therapeutic interventions in different illnesses like Alzheimer´s disease, viral infections and different tumors. Regarding the ...
Critical role of hippocampal muscarinic acetylcholine receptors on memory reconsolidation in mice
(Academic Press Inc Elsevier Science, 2021-01)
Over the years, experimental and clinical evidence has given support to the idea that acetylcholine (Ach) plays an essential role in mnemonic phenomena. On the other hand, the Hippocampus is already known to have a key ...
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake
(Wiley-Blackwell, 2008-12-01)
Background and purpose: Recent evidence has suggested that pilocarpine (ACh receptor agonist) injected peripherally may act centrally producing salivation and hypertension. In this study, we investigated the effects of ...
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake
(Wiley-Blackwell, 2008-12-01)
Background and purpose: Recent evidence has suggested that pilocarpine (ACh receptor agonist) injected peripherally may act centrally producing salivation and hypertension. In this study, we investigated the effects of ...
The Snake Venom Peptide Bj-PRO-7a Is a M1 Muscarinic Acetylcholine Receptor Agonist
(WILEY-BLACKWELL, 2011)
Proline-rich peptides from Bothrops jararaca venom (Bj-PRO) were characterized based on the capability to inhibit the somatic angiotensin-converting enzyme. The pharmacological action of these peptides resulted in the ...
Functional muscarinic receptors in cultured skeletal muscle
(Academic Press Inc., 1996)
We studied the influence of muscarinic and nicotinic stimulation on both phosphoinositide metabolism and intracellular calcium levels in rat skeletal muscle primary cultures. Both nicotine and muscarine induced an increase ...