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Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors.
(Ivyspring International Publisher, 2020)
Knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, supporting a selective therapy against different types of cancer. In ...
Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway
(Taylor & Francis, 2017)
Mitochondrial functions and melatonin: a tour of the reproductive cancers
(2019-03-15)
Cancers of the reproductive organs have a strong association with mitochondrial defects, and a deeper understanding of the role of this organelle in preneoplastic–neoplastic changes is important to determine the appropriate ...
The β2-adrenergic agonist salbutamol inhibits migration, invasion and metastasis of the human breast cancer MDA-MB- 231 cell line
(Bentham Science Publishers, 2017-09)
Breast cancer is the most diagnosed and the major cause of cancer death in women worldwide. Metastasis is the main cause of these deaths. The metastatic cascade involves multiple steps and it has been described that ...
The β2-adrenergic agonist salbutamol inhibits migration, invasion and metastasis of the human breast cancer MDA-MB-231 cell line
(Bentham Science Publishers, 2017)
Background: Breast cancer is the most diagnosed and the major cause of cancer death in women worldwide. Metastasis is the main cause of these deaths. The metastatic cascade involves multiple steps and it has been described ...
Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats
(2020-05-19)
Clinical investigations suggest that melatonin suppression and circadian dysfunction may be related to cancer development in shift workers. Studies also show that melatonin suppression after pinealectomy increases cancer ...
Complex mitochondrial dysfunction induced by TPP+-gentisic acid and mitochondrial translation inhibition by doxycycline evokes synergistic lethality in breast cancer cells
(MDPI, 2020)
The mitochondrion has emerged as a promising therapeutic target for novel cancer treatments because of its essential role in tumorigenesis and resistance to chemotherapy. Previously, we described a natural compound, ...
Molecular iodine inhibits the expression of stemness markers on cancer stem-like cells of established cell lines derived from cervical cancer
(2018)
Background: Cancer stem cells (CSC) are characterized by deregulated self-renewal, tumorigenicity, metastatic potential, aberrant stemness signaling pathways, resistance to conventional therapy, and the ability to give ...
Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth
(Wiley-Blackwell, 2017)
Lectins have been used at length for basic research and clinical applications. New insights into the molecular recognition properties enhance our basic understanding of carbohydrate-protein interactions and aid in the ...