Buscar
Mostrando ítems 21-30 de 57
Retina stem cells, hopes and obstacles
(Baishideng Publishing, 2021-10-26)
Retinal degeneration is a major contributor to visual dysfunction worldwide. Although it comprises several eye diseases, loss of retinal pigment epithelial (RPE) and photoreceptor cells are the major contributors to their ...
Sphingolipids as critical players in retinal physiology and pathology
(American Society for Biochemistry and Molecular Biology, 2021-01)
Sphingolipids have emerged as bioactive lipids involved in the regulation of many physiological and pathological processes. In the retina, they have been established toparticipate in numerousprocesses, suchas neuronal ...
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation
(2023-12)
Background: Major retinal degenerative diseases, including age-related macular degeneration, diabetic retinopathy and retinal detachment, are associated with a local decrease in oxygen availability causing the formation ...
NeuroD1 is required for survival of photoreceptors but not pinealocytes: Results from targeted gene deletion studies
(Wiley Blackwell Publishing, Inc, 2012-10)
NeuroD1 encodes a basic helix-loop-helix transcription factor involved in the development of neural and endocrine structures, including the retina and pineal gland. To determine the effect of NeuroD1 knockout in these ...
Light Regulation of Plant Defense
(Annual Reviews, 2014-04)
Precise allocation of limited resources between growth and defense is critical for plant survival. In shade-intolerant species, perception of competition signals by informational photoreceptors activates shade-avoidance ...
Dimer asymmetry and light activation mechanism in brucella blue-light sensor histidine kinase
(American Society for Microbiology, 2021-03)
The ability to sense and respond to environmental cues is essential for adaptation and survival in living organisms. In bacteria, this process is accomplished by multidomain sensor histidine kinases that undergo ...
Oxidative stress in retinal degeneration promoted by constant LED light
(Frontiers Media S.A., 2019-01)
Light pollution by artificial light, might accelerate retinal diseases and circadian asynchrony. The excess of light exposure is a growing problem in societies, so studies on the consequences of long-term exposure to low ...