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Effect of Bacterial Infection on Ghrelin Receptor Regulation in Periodontal Cells and Tissues
(2022-03-01)
The effect of bacterial infection on the expression of growth hormone secretagogue receptor (GHS-R) was investigated in periodontal cells and tissues, and the actions of ghrelin were evaluated. GHS-R was assessed in ...
Ghrelin antagonist D‐Lys3‐GHRP‐6 counteract ghrelin effects in bovine cumulus‐oocytes complexes matured in vitro
(Wiley Blackwell Publishing, Inc, 2021-09)
Ghrelin is a gut hormone related to energy balance and reproductive functions. The aim of this study was to evaluate the effect of ghrelin antagonist D-Lys3-GHRP-6 (GA) as a potential agent that prevents ghrelin effects ...
The actions of ghrelin in the paraventricular nucleus: Energy balance and neuroendocrine implications
(Blackwell Publishing, 2019-04-22)
Ghrelin is a peptide mainly produced and secreted by the stomach. Since its discovery, the impact of ghrelin on the regulation of food intake has been the most studied function of this hormone; however, ghrelin affects a ...
Hypothalamic ghrelin treatment modulates NPY-but not CRH-ergic activity in adrenalectomized rats subjected to food restriction: Evidence of a novel hypothalamic ghrelin effect
(Humana Press, 2006-12)
It has been proposed that ghrelin induces food intake by a mechanism due to the stimulation of hypothalamic NPY-ergic activity. It is recognized that bilateral adrenalectomy (ADX) enhances hypothalamic CRHergic function ...
Ghrelin Facilitates GLUT2-, SGLT1-and SGLT2-mediated Intestinal Glucose Transport in Goldfish (Carassius auratus)
(Nature Publishing Group, 2017-03)
Glucose homeostasis is an important biological process that involves a variety of regulatory mechanisms. This study aimed to determine whether ghrelin, a multifunctional gut-brain hormone, modulates intestinal glucose ...
GOAT induced ghrelin acylation regulates hedonic feeding
(Academic Press Inc Elsevier Science, 2012-11)
Ghrelin is an orexigenic hormone that regulates homeostatic and reward-related feeding behavior. Recent evidence indicates that acylation of ghrelin by the gut enzyme ghrelin O-acyl transferase (GOAT) is necessary to render ...
Ghrelin and its interactions with growth hormone, leptin and orexins: implications for the sleep-wake cycle and metabolism
(Elsevier, 2014-02)
Several studies have shown that ghrelin administration promotes wakefulness in rodents, while in human males it induces sleep but has no effect in women. Ghrelin also plays an important role in metabolism and appetite ...