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Role of Autophagy in the Microenvironment of Oral Squamous Cell Carcinoma
(Frontiers Media, 2020)
Oral squamous cell carcinoma, the most common type of oral cancer, affects more than 275,000 people per year worldwide. Oral squamous cell carcinoma is very aggressive, as most patients die after 3 to 5 years post-diagnosis. ...
Characterization of PAR1 and FGFR1 expression in invasive breast carcinomas: Prognostic significance
(SPANDIDOS PUBL LTDATHENS, 2012)
Breast cancer is the most common cause of cancer mortality among women worldwide. Among the several factors associated with breast cancer development, angiogenesis plays an essential role and has currently emerged as a ...
Interleukin-6 receptor in spindle-shaped stromal cells, a prognostic determinant of early breast cancer
(Karger, 2016-10)
Spindle-shaped stromal cells, like carcinoma-associated fibroblasts and mesenchymal stem cells, influence tumor behavior and can serve as parameters in the clinical diagnosis, therapy, and prognosis of early breast cancer. ...
In Situ Overexpression of Matricellular Mechanical Proteins Demands Functional Immune Signature and Mitigates Non-Small Cell Lung Cancer Progression
(2021-08-16)
Non-small cell lung carcinoma (NSCLC) is a complex cancer biome composed of malignant cells embedded in a sophisticated tumor microenvironment (TME) combined with different initiating cell types, including immune cells and ...
Melatonin regulates angiogenic and inflammatory proteins in MDA-MB-231 cell line and in co-culture with cancer-associated fibroblasts
(2016-11-01)
Background: Cancer-associated fibroblast (CAFs) are the most abundant cells in the tumor microenvironment, able to secrete growth factors and act on tumor progression. Melatonin is associated with several mechanisms of ...
Reactive Stroma In The Prostate During Late Life: The Role Of Microvasculature And Antiangiogenic Therapy Influences
(WILEY-BLACKWELLHOBOKEN, 2015)
Scanning and transmission electron microscopy of transformed Vero cells, with altered in vitro growth characteristics
(Editrice Compositori BolognaBolognaItália, 1996)
Inoculated mammary carcinoma-associated fibroblasts: contribution to hormone independent tumor growth
(BioMed Central, 2010)
Increasing evidence has underscored the role of carcinoma associated fibroblasts (CAF) in tumor growth. However, there are controversial data regarding the persistence of inoculated CAF within the tumors. We have developed ...