Buscar
Mostrando ítems 11-20 de 2065
A systematic scoping review of the genetic ancestry of the Brazilian population
(Sociedade Brasileira de Genética, 2020)
A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: the Brazilian set
(European Society of Human GeneticsBrasil, 2015-09)
The Brazilian population is considered to be highly admixed. The main contributing ancestral populations were European and African, with Amerindians contributing to a lesser extent. The aims of this study were to provide ...
Unsupervised detection of ancestry tracks with the GHap r package
(2020-01-01)
The identification of ancestry tracks is a powerful tool to assist the inference of evolutionary events in the genomes of animals and plants. However, algorithms for ancestry track detection typically require labelled ...
Neither self-reported ethnicity nor declared family origin are reliable indicators of genomic ancestry
(2016-06-01)
Ancestry information can be useful in investigations of diseases with a genetic or infectious background. As the Brazilian population is highly admixed physical traits tend to be poor indicators of ancestry. The assessment ...
Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations
(National Academy of Sciences, 2015)
While South Americans are underrepresented in human genomic diversity studies, Brazil has been a classical model for population genetics studies on admixture.We present the results of the EPIGEN Brazil Initiative, the most ...
Development of a small panel of SNPs to infer ancestry in chileans that distinguishes Aymara and Mapuche components
(Sociedad de Biología de Chile, 2020)
Background Current South American populations trace their origins mainly to three continental ancestries, i.e. European, Amerindian and African. Individual variation in relative proportions of each of these ancestries may ...
Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos
(Sociedad Médica de Santiago, 2014)
Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population
(Elsevier, 2021)
Alzheimer disease (AD) is the leading cause of dementia in the elderly and occurs in all ethnic and racial groups. The apolipoprotein E (ApoE) ε4 is the most significant genetic risk factor for late-onset AD and shows the ...