Buscar
Mostrando ítems 1261-1270 de 1982
Role of Ca, Fe, Cu and Zn in breast cancer: Study by X-ray fluorescence techniques and immunohistochemical analysis
(2013-07-01)
In recent years, several studies have shown that concentrations of trace elements are altered in neoplastic breast tissues. However, the microenvironment and metabolic changes caused by tumors are complex and still not ...
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness
(Wiley-Blackwell, 2006-09-01)
Invasive behavior is the pathological hallmark of malignant gliomas, being responsible for the failure of surgery, radiation, and chemotherapy. Matrix metalloproteinases (MMPs) are essential for proper ECM remodeling and ...
Gastric cancer: Genetic and molecular [Cáncer gástrico: Alteraciones genéticas y moleculares]
(2011)
In this work, the genetic and molecular alterations involved in gastric carcinogenesis are shown; the affected genes are those that encoded for matrix metalloproteinases, cell growth factors and receptors, oncogenes, tumor ...
Histological evaluation and gene expression profiling of autophagy-related genes for cartilage of young and senescent rats
(MDPI AG, 2020-11-02)
Autophagy is a cellular mechanism that protects cells from stress by digesting non-functional cellular components. In the cartilage, chondrocytes depend on autophagy as a principal mechanism to maintain cellular homeostasis. ...
Role of Ca, Fe, Cu and Zn in breast cancer: Study by X-ray fluorescence techniques and immunohistochemical analysis
(2013-07-01)
In recent years, several studies have shown that concentrations of trace elements are altered in neoplastic breast tissues. However, the microenvironment and metabolic changes caused by tumors are complex and still not ...
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness
(Wiley-Blackwell, 2006-09-01)
Invasive behavior is the pathological hallmark of malignant gliomas, being responsible for the failure of surgery, radiation, and chemotherapy. Matrix metalloproteinases (MMPs) are essential for proper ECM remodeling and ...
P504S expressing circulating prostate cells as a marker for prostate cancer
(CIENCIAS, 2010)
Prostate cancer is the most commonly diagnosed cancer in men and the second leading cause of cancer deaths. The serum prostate specific antigen (PSA) is the only biomarker routinely used in screening. The aim of this study ...
Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions
(CIENCIAS, 2008)
Objective. Many matrix metalloproteinases ( MMPs) have been associated with periodontal tissue destruction during chronic and apical periodontitis. The aim of this study was to determine gelatinolytic activity in gingival ...
Haplotypes of susceptibility to chronic periodontitis do not influence MMP-8 levels or the outcome of non-surgical periodontal therapy
(2014)
Introduction: Chronic periodontitis (CP) is a multifactorial condition, presenting immunoinflammatory reaction, in which a myriad of molecules including cytokines and matrix metalloproteinases (MMPs) interplays, ...
A Novel Chemically Modified Curcumin Reduces Severity of Experimental Periodontal Disease in Rats: Initial Observations
(Hindawi Publishing Corporation, 2014-01-01)
Tetracycline-based matrix metalloproteinase-(MMP-) inhibitors are currently approved for two inflammatory diseases, periodontitis and rosacea. The current study addresses the therapeutic potential of a novel pleiotropic ...