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Mostrando ítems 1201-1210 de 1982
Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat
(Biomed Central Ltd, 2007-07-10)
Background: Relaxin is the endogenous ligand of the G-protein coupled receptor RXFP1 previously known as LGR7. in humans relaxin can also activate, but with lower affinity, the closely related receptor for the insulin-like ...
Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression
(American Association for Cancer Research, 2012-10)
During progression from single cancer cells to a tumor mass and metastases, tumor cells send signals that can subvert their tissue microenvironment. These signals involve soluble molecules and various extracellular vesicles, ...
Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4t1 breast adenocarcinoma cell
(Karger, 2005-12-08)
The 25-kDa heat shock protein (Hsp25) is associated with various malignancies and is expressed at high levels in biopsies as well as circulating in the serum of breast cancer patients. In this study, we used RNA interference ...
Fortalecimento muscular na osteoartrite de joelho de ratos: implicações locais e sistêmicas
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Fisioterapia - PPGFt, 2014-01-22)
Osteoarthritis is the most common disease among the elderly ostemioarticular, being of great relevance for public health and for studies related to aging processes. In this context, the muscle strengthening becomes important ...
Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts
(2015)
Objectives: The human antimicrobial peptide cathelicidin (LL-37) possesses anti-inflammatory properties that may contribute to attenuating the inflammatory process associated with chronic periodontitis. Plant polyphenols, ...
Protective effects of desipramine on alveolar bone in experimental periodontitis
(Wiley-Blackwell, 2020-06-05)
Background Desipramine is a tricyclic antidepressant with immune-modulatory activity, whose effects on ligature-induced periodontitis are yet to be investigated. Hence, its actions on alveolar bone resorption, gingival ...
Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice
(2016-09-01)
The pathogenesis of dermonecrosis induced by the venom of the African spitting cobra Naja nigricollis was investigated in a mouse model. Intradermal injection of venom induced a macroscopic necrotic lesion. Histological ...
Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice
(2016-09-01)
The pathogenesis of dermonecrosis induced by the venom of the African spitting cobra Naja nigricollis was investigated in a mouse model. Intradermal injection of venom induced a macroscopic necrotic lesion. Histological ...
Matriz extracelular e enzimas degradatórias na hematopoese e doenças onco-hematológicas
(Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2008-10-01)
The extracellular matrix (ECM) is a complex structure composed of collagens, proteoglycans, glycosaminoglycans and adhesive glycoproteins. Interactions between the cells and the ECM are crucial to determine cell behavior, ...