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Immune-neuroendocrine and metabolic disorders in human and experimental T. cruzi infection: New clues for understanding Chagas disease pathology
(Elsevier Science, 2020-03)
Studies in mice undergoing acute Trypanosoma cruzi infection and patients with Chagas disease, led to identify several immune-neuroendocrine disturbances and metabolic disorders. Here, we review relevant findings concerning ...
Periprostatic adipose tissue microenvironment: metabolic and hormonal pathways during prostate cancer progression
(Frontiers Media, 2022-04)
The periprostatic adipose tissue (PPAT) is a site of invasion of prostate cancer (PCa) and is part of the microenvironment. It was shown that PPAT secretes factors and fatty acids (FAs) that alter the microenvironment of ...
Influence of prenatal stress on metabolic abnormalities induced by postnatal intake of a high-fat diet in BALB/c mice
(Cambridge University Press, 2020-10)
Prenatal insults during fetal development result in increased likelihood of developing chronic disease. Obesity, the biggest risk factor for the development of metabolic disease, is affected by several genetic and environmental ...
Inositolphosphoceramide metabolism in Trypanosoma cruzi as compared with other trypanosomatids
(Wiley Blackwell Publishing, Inc, 2011-03)
Chagas disease is caused by Trypanosoma cruzi and is endemic to North, Central and South American countries. Current therapy against this disease is only partially effective and produces adverse side effects. Studies on ...
Adipokines, Cardiovascular Risk, and Therapeutic Management in Obesity and Psoriatic Arthritis
(Frontiers Research Foundation, 2021-02-10)
Psoriatic arthritis is a chronic inflammatory disease with skin and joint pathology as the dominant characteristics. Scientific evidence supports its systemic nature and relevant relationship with obesity, metabolic syndrome, ...
Dysregulated network of immune, endocrine and metabolic markers is associated to more severe human chronic chagas cardiomyopathy
(Karger, 2018-12)
Individuals who are infected with Trypanosoma cruzi develop chronic Chagas cardiomyopathy (CCC), which is a complication involving a series of immune pathogenetic mechanisms, although an association between immune and ...