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Mostrando ítems 11-20 de 536
Developing an elegant and integrated electrochemical-theoretical approach for detection of DNA damage induced by 4-nonylphenol
(Elsevier, 2019-10)
In this work, a novel biosensor was fabricated for detection of DNA damage induced by 4-nonylphenol (NP) and also determination of NP. To achieve this goal, a glassy carbon electrode (GCE) was modified with chitosan (Chit), ...
Influence of dietary fish oil supplementation on DNA damage in peripheral blood lymphocytes of nine healthy dogs
(Wiley, 2021-06)
Background: Fish oil (FO) supplementation as a source of omega 3 fatty acids is associated with beneficial effects on health. However, high unsaturated fatty acid content in thediet could result in increased lipid peroxidation ...
DNA damaging potential of Ganoderma lucidum extracts
(Elsevier Ireland, 2018-05-10)
Ethnopharmacological relevance: Ganoderma lucidum (Lingzhi or Reishi) is a medicinal mushroom historically used in Asian countries to treat a wide variety of diseases and prolong life. In the last years, G. lucidum has ...
Measuring human DNA degradation and gender detection in forensic DNA samples by q-PCR/HRM analysis
(Elsevier Science, 2017-12)
Human DNA quantification, DNA degradation assessment and gender determination are key aspects in most field of human DNA analysis. The assay reported here is a tri-plex Real Time quantitative PCR reaction followed by high ...
Differential contribution of HP1 proteins to DNA end resection and homology-directed repair
(Taylor & Francis, 2013-02)
Heterochromatin protein 1 paralogs (HP1α, β and γ in mammals) are not only central in heterochromatin organization, but have also been linked to transcriptional activation at euchromatic regions, maintenance of telomere ...
The secretome of non-tumorigenic mammary cells MCF-10A elicits DNA damage in MCF-7 and MDA-MB-231 breast cancer cells
(Pergamon-Elsevier Science Ltd, 2020-11)
Radiotherapy is used in breast cancer to destroy tumor cells lingering after surgery. It is accepted that lethal effects of ionizing radiation occur as a result of damage to DNA in irradiated (IR) cells. However, response ...
Evaluation of imazethapyr-induced DNA oxidative damage by alkaline Endo III- and Fpg-modified single-cell gel electrophoresis assay in Hypsiboas pulchellus tadpoles (Anura, Hylidae)
(Academic Press Inc Elsevier Science, 2017-08)
Imazethapyr (IMZT) is a selective postemergent herbicide with residual action. Available data analyzing its effects in aquatic vertebrates are scarce. In previous studies, we demonstrated that IMZT induces lesions into the ...
DNA damage induced by photoexcited bare and loaded Microporous Coordination Polymers
(Royal Society of Chemistry, 2015-05)
We report on interactions of cell free double-stranded DNA (dsDNA) with a selected subgroup of Microporous Coordination Polymers (MCPs). In particular, we have studied the influence of different metal ion constituents and ...
ADP-ribosylation: From molecular mechanisms to human disease
(Sociedade Brasileira de Genética, 2020-01)
Post-translational modification of proteins by ADP-ribosylation, catalysed by poly (ADP-ribose) polymerases (PARPs) using NAD+ as a substrate, plays central roles in DNA damage signalling and repair, modulates a range of ...