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Mostrando ítems 41-48 de 48
Lipids From Trypanosoma cruzi Amastigotes of RA and K98 Strains Generate a Pro-inflammatory Response via TLR2/6
(Frontiers Media SA, 2018-05)
Lipids from microorganisms are ligands of Toll like receptors (TLRs) and modulate the innate immune response. Herein, we analyze in vitro the effect of total lipid extracts from Trypanosoma cruzi amastigotes of RA and K98 ...
Tumor necrosis Factor Receptor-1 (p55) deficiency attenuates tumor growth and intratumoral angiogenesis and stimulates CD8+ T cell function in melanoma
(MDPI, 2020-11)
The role of tumor necrosis factor-α (TNF-α) in shaping the tumor microenvironment is ambiguous. Consistent with its uncertain role in melanoma, TNF-α plays a dual role, either acting as a cytotoxic cytokine or favoring a ...
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor
(Wiley Blackwell Publishing, Inc, 2012-01)
Background and Purpose: DF 2156A is a new dual inhibitor of IL-8 receptors CXCR1 and CXCR2 with an optimal pharmacokinetic profile. We characterized its binding mode, molecular mechanism of action and selectivity, and ...
Phenolics with Leishmanicidal and Immunomodulatory Properties
(Universidad Militar Nueva Granada, 2014)
Pertussis: reemerging diseasePertussis: enfermedad reemergentePertussis: doença reemergente
(Universidad Militar Nueva Granada, 2017)
Pertussis: reemerging diseasePertussis: enfermedad reemergentePertussis: doença reemergente
(Universidad Militar Nueva Granada, 2017)