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Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice
(Nature Research Journals, 2018-06)
Endocrine disrupting chemicals are long suspected to impair reproductive health. Bisphenol A (BPA) has estrogenic activity and therefore the capacity of interfering with endocrine pathways. No studies dissected its short-term ...
Exposure of neonatal female rats to bisphenol A disrupts hypothalamic LHRH pre-mRNA processing and estrogen receptor alpha expression in nuclei controlling estrous cyclicity
(Elsevier Science, 2010-12)
This study examines the effects of neonatal exposure to the endocrine disruptor bisphenol A (BPA) on the neural network that controls estrous cyclicity. From postnatal day 1 (PND1) to PND7, female pups were injected with ...
Biodegradation of bisphenol-A (BPA) in activated sludge batch reactors: Analysis of the acclimation process
(Elsevier, 2013-11-28)
In this work the effect of (a) the sludge age (SA) and the acclimation strategy on the acclimation process of activated sludge (AS) to bisphenol A (BPA), (b) the presence of biogenic substrates on the degradation of BPA, ...
Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats
(Elsevier Ireland, 2018-03)
Bisphenol A (BPA) is a component of polycarbonate plastics, epoxy resins and polystyrene found in many common products. Several reports revealed potent in vivo and in vitro effects. In this study we analyzed the effects ...
Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor α transcripts with alternative 5′-untranslated regions in the female rat preoptic area
(BioScientifica, 2007-12)
The xenoestrogen bisphenol A (BPA) is commonly ingested by humans. We examined the effects of neonatal exposure to low versus high doses of BPA over the control of estrogen receptor alpha (ERalpha) expression in the preoptic ...
Ovarian dysfunctions in adult female rat offspring born to mothers perinatally exposed to low doses of bisphenol A
(Pergamon-Elsevier Science Ltd, 2016-02)
The study of oral exposure to the environmental estrogen bisphenol A (BPA) during the perinatal periodand its effects on ovarian functionality in adulthood has generated special interest. Thus, our objectivewas to investigate ...
Neonatal exposure to bisphenol A or diethylstilbestrol alters the ovarian follicular dynamics in the lamb
(Pergamon-Elsevier Science Ltd, 2011-11)
We hypothesized that neonatal xenoestrogen exposure affects the ovarian follicular dynamics in lambs. Female lambs were exposed from postnatal day (PND) 1-14 to low doses of diethylstilbestrol (DES) or bisphenol A (BPA). ...
Developmental exposure to bisphenol A alters the differentiation and functional response of the adult rat uterus to estrogen treatment
(Pergamon-Elsevier Science Ltd, 2015-04)
We assessed the long-term effect of perinatal exposure to bisphenol A (BPA) on the rat uterus and the uterine response to estrogen (E2) replacement therapy. BPA (0.5 or 50. μg/kg/day) was administered in the drinking water ...
Perinatal exposure to bisphenol A modifies the transcriptional regulation of the β-Casein gene during secretory activation of the rat mammary gland
(Elsevier Ireland, 2017-01)
With the aim to analyze whether bisphenol A (BPA) modifies β-Casein (β-Cas) synthesis and transcriptional regulation in perinatally exposed animals, here, pregnant F0 rats were orally exposed to 0, 0.6 or 52 μg BPA/kg/day ...