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Mutagenic and carcinogenic potential of a textile azo dye processing plant effluent that impacts a drinking water source
(Elsevier B.V., 2007-01-10)
Recently a textile azo dye processing plant effluent was identified as one of the sources of mutagenic activity detected in the Cristais River, a drinking water source in Brazil [G.A. Umbuzeiro, D.A. Roubicek, C.M. Rech, ...
Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis
(Japanese Journal Of Cancer Research : Gann, 1999)
Natural killer (NK) cell activity was evaluated after the initiation and promotion steps in a medium-term multi-organ bioassay for carcinogenesis. NK cell activity was assessed in vitro by Cr51 release assay at the 4th and ...
Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
(Nature, 2018)
Background: Periodontal pathogens have been linked to oral and gastrointestinal (orodigestive) carcinogenesis. However, the
exact mechanisms remain unknown. Treponema denticola (Td) is associated with severe periodontitis, ...
Reduction of β-Glucuronidase and nitroreductase activity by yoghurt in a murine colon cancer model
(Sociedad Latinoamericana de Microscopía Electrónica; Centro Regional de Investigaciones Científicas y Tecnológicas, 2005-04)
Yoghurt feeding inhibits induced colon cancer in mice. Several studies showed the immunomodulatory effect of yoghurt which can explain this inhibition. It is possible that yoghurt bacteria can also affect gut flora enzymes ...
Mutación del gen p53 en el cáncer de colon y recto
(Sociedad Médica de Santiago, 2000)
Probióticos e prebióticos na atenção primária ao câncer de cólon
(Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)Colégio Brasileiro de Cirurgia Digestiva (CBCD)Sociedade Brasileira de Motilidade Digestiva (SBMD)Federação Brasileira de Gastroenterologia (FBG)Sociedade Brasileira de Hepatologia (SBH)Sociedade Brasileira de Endoscopia Digestiva (SOBED), 2010-03-01)
CONTEXTO: As neoplasias de cólon são a terceira forma mais comum de câncer atualmente. Seus tratamentos ainda estão associados a elevado risco de complicações, ressaltando, assim, a necessidade de elaborar novas estratégias ...
MiR-1 Is a Tumor Suppressor in Thyroid Carcinogenesis Targeting CCND2, CXCR4, and SDF-1 alpha
(ENDOCRINE SOC, 2011)
Context: Micro-RNA have emerged as an important class of short endogenous RNA that act as posttranscriptional regulators of gene expression and are constantly deregulated inhumancancer. MiR-1 has been found down-regulated ...
Sorting Nexin 1 Down-Regulation Promotes Colon Tumorigenesis
(American Association for Cancer Research, 2006-12)
PURPOSE: Colon cancer is one of the most common human malignancies, yet studies have only begun to identify the multiple mechanisms that underlie the development of this tumor. In this study, we have identified a novel ...
Obesity-Induced Increase in Tumor Necrosis Factor-alpha Leads to Development of Colon Cancer in Mice
(W B Saunders Co-elsevier IncPhiladelphiaEUA, 2012)