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Clinical features of tic-related obsessive-compulsive disorder: results from a large multicenter study
(Cambridge University Press, 2012-06-01)
Objective. To evaluate the clinical features of obsessive-compulsive disorder (OCD) patients with comorbid tic disorders (TD) in a large, multicenter, clinical sample.Method. A cross-sectional study was conducted that ...
Serotonergic neurons in the median raphe nucleus regulate inhibitory avoidance but not escape behavior in the rat elevated T-maze test of anxiety
(Springer, 2005-06-01)
Rationale: A wealth of evidence supports the involvement of the serotonergic neurons of the median raphe nucleus (MRN) in anxiety. However, it is presently unclear whether serotonergic pathways arising from this nucleus ...
Clinical features of pure obsessive-compulsive disorder
(2013-10-01)
Objective Psychiatric comorbidity is the rule in obsessive-compulsive disorder (OCD); however, very few studies have evaluated the clinical characteristics of patients with no co-occurring disorders (non-comorbid or pure ...
Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
(SAGE PUBLICATIONS LTD, 2011)
Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic properties. However, no study to date has investigated the effects of this compound on human pathological anxiety ...
Effects of the essential oil from Citrus aurantium L. in experimental anxiety models in mice
(Elsevier B.V., 2006-03-06)
Citrus aurantium L. is popularly used to treat anxiety, among other indications suggesting central nervous system action. Previous studies showed anxiolytic effect in the essential oil from peel in mice evaluated on the ...
Diretrizes da Associação Médica Brasileira para o diagnóstico e diagnóstico diferencial do transtorno de ansiedade social
(Associação Brasileira de Psiquiatria - ABP, 2010)
OBJETIVO: O transtorno de ansiedade social é o transtorno de ansiedade mais comum, apresenta curso crônico, frequentemente sem remissões, sendo comumente associado com importante prejuízo funcional e comprometimento ...
The median raphe nucleus in anxiety revisited
(Sage Publications Ltd, 2013-12-01)
Although the role of the median raphe nucleus (MRN) in the regulation of anxiety has received less attention than that of the dorsal raphe nucleus (DRN) there is substantial evidence supporting this function. Reported ...
Dorsal periaqueductal gray stimulation facilitates anxiety-, but not panic-related, defensive responses in rats tested in the elevated T-maze
(Associação Brasileira de Divulgação Científica, 2012)
The escape response to electrical or chemical stimulation of the dorsal periaqueductal gray matter (DPAG) has been associated with panic attacks. In order to explore the validity of the DPAG stimulation model for the study ...
The hypothalamic-pituitary-adrenal axis in anxiety and panic
(Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo, 2010)
This review article focuses on the differential activation of the hypothalamic-pituitary-adrenal (HPA) axis in generalized anxiety and panic. The results of experimental studies that assayed adrenocorticotropic hormone, ...