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Sublethal doses of dinophysistoxin-1 and okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences
(Elsevier Ltd, 2017)
© 2016 Elsevier LtdOne of the proposed mechanisms to explain why Diarrhetic Shellfish Poison (DSP) toxins are tumor promoters is founded on the capacity of these toxins to increase TNF-α secretion. Although macrophages are ...
Elevated Systemic Inflammatory Burden and Cardiovascular Risk in Young Adults with Endodontic Apical Lesions
(Elsevier Inc., 2019)
Introduction: The aim of this study was to assess whether apical lesions are associated with inflammatory serum markers of cardiovascular risk, especially high-sensitivity C-reactive protein (hsCRP), in young adults. ...
Host-pathogen interactions in progressive chronic periodontitis
(Sage, 2011-10)
Periodontitis is an infection characterized by the occurrence of supporting tissue destruction with an episodic nature. Disease progression is often determined by the loss of attachment level or alveolar bone, and sequential ...
Subclinical concentrations of chlorhexidine inhibit gelatinase activity of carious dentine in vitro
(Australian Dental Association, 2014)
Background: There is evidence that dentine matrix gelatinases are involved in the destruction of carious dentine after
demineralization by bacterial acids. It has also been observed that chlorhexidine, in very low ...
Oxidative stress in the local and systemic events of apical periodontitis
(Frontiers Media SA, 2017)
Oxidative stress is involved in the pathogenesis of a variety of inflammatory disorders. Apical periodontitis (AP) usually results in the formation of an osteolytic apical lesion (AL) caused by the immune response to ...
Collagenase-2 (MMP-8) as a point-of-care biomarker in periodontitis and cardiovascular diseases. Therapeutic response to non-antimicrobial properties of tetracyclines
(Elsevier, 2011-02)
Neutrophil collagenase or collagenase-2 (matrix metalloproteinase [MMP]-8) belongs to the collagenase
subgroup of the MMP superfamily of calcium- and zinc-dependent neutral proteinases. MMP-8 is catalytically
the most ...
DL-2-hydroxyisocaproic acid attenuates inflammatory responses in a murine Candida albicans biofilm model
(2014)
Chronic biofilm infections are often accompanied by a chronic inflammatory response, leading to impaired healing and increased, irreversible damage to host tissues. Biofilm formation is a major virulence factor for Candida ...
Diagnostic accuracy for apical and chronic periodontitis biomarkers in gingival crevicular fluid: an exploratory study
(Wiley, 2016)
AimThe aim of this study was to assess the levels and diagnostic accuracy of a set of potential biomarkers of periodontal tissue metabolism in gingival crevicular fluid (GCF) from patients with chronic periodontitis (CP) ...
In-vitro study of gonadotrophin signaling pathways in human granulosa cells in relation to progesterone receptor expression
(Elsevier, 2017)
In humans, data on gonadotrophin-activated (LH, HCG and FSH) progesterone receptor expression and signalling pathways involved in matrix metalloproteinases (MMPs) expression presumably linked to the follicle rupture, are ...
Overexpression of MMPs, cytokines, and RANKL/OPG in temporomandibular joint osteoarthritis and their association with joint pain, mouth opening, and bone degeneration: A preliminary report
(Wiley, 2020)
Objective This study aimed to determine the expression of distinct matrix metalloproteinases, cytokines, and bone resorptive factors in temporomandibular joint osteoarthritis (TMJ-OA) patients and their association with ...