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Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa
(2010)
The immunoreactivity of EchiTAb-Plus-ICP, an antivenom developed for the treatment of snakebite envenoming in sub-Saharan Africa, to venoms of seven Echis and Bitis species, was assessed by “antivenomics.” This proteomic ...
Isolation from a polyvalent antivenom of antibodies to a myotoxin in Bothrops asper snake venom
(1985)
Antibodies against Bothrops asper rmyotoxin were purified from a polyvalent antivenom by affinity chromatography . These antibodies neutralized most of the myotoxic activity of crude B. asper venom, as judged by histologic ...
Venom, venomics, antivenomics
(2009)
Venoms comprise mixtures of peptides and proteins tailored by Natural Selection to act on vital systems
of the prey or victim. Here we review our proteomic protocols for uncoiling the composition,
immunological profile, ...
The importance of breast-feeding for optimal child health and well-being
(Clinical nutrition, Manual of clinical nutrition; 3 (1) (Suppl 3): 28-33, 1984-01)
Breast-fed infants can thrive even under unhygienic conditions in areas of extreme poverty. The anti-infectious properties of human milk account for the very high resistance of the nursing infant to infection in general ...
Highly individual patterns of virus‑immune IgG effector responses in humans
(2016-05-18)
t IgG responses are fundamental to adaptive
immunity and document immunological memory of previous
pathogen encounter. While specific antigen recognition
is mediated by the variable F(ab′)2 domain of IgG, various
effector ...
Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses
(2016-11)
The application of proteomic tools to the study of snake venoms has led to an impressive growth in the
knowledge about their composition (venomics), immunogenicity (antivenomics), and toxicity (toxicovenomics).
About ...
Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: proteome, toxicity, and cross-neutralization by antivenom
(2016-03)
In Colombia, nearly 2.8% of the 4200 snakebite accidents recorded annually are inflicted by coral snakes (genus
Micrurus). Micrurus dumerilii has a broad distribution in this country, especially in densely populated ...
Similar effectiveness of Fab and F(ab')2 antivenoms in the neutralization of hemorrhagic activity of Vipera berus snake venom in mice
(1996)
The ability of two antivenoms to Vipera spp., consisting of Fab (Therapeutic Antibodies), or of F(ab′)2 (Zagreb Institute of Immunology) antibody fragments, to neutralize the hemorrhagic activity of Vipera berus snake venom ...
Replication of Influenza A and B Viruses in Human Diploid Cells
(J Gen Virol 64: p 471-475, 1983-09-20)
Under optimal conditions, of high multiplicities of infection and with trypsin
included in the medium throughout the incubation period, high yields of infectious
influenza A and B viruses (106-5 p.f.u./ml) and of ...
Host response to Bothrops asper snake venom: analysis of edema formation, inflammatory cells, and cytokine release in a mouse model
(1993)
As part of tle characterization of the host reactivity to the venom of Bothrops
asper, we investigated the inflammatory responses in the mouse footpad model.
The subcutaneously iniected venom induced a rapid increase of ...