artículo
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans
Fecha
2004Registro en:
10.1038/sj.jhh.1001646
WOS:000188224500008
Autor
Braun, S.
Chamorro, G.
Córdova, S.
Fardella, C.
Godoy, I.
Jalil, J.E.
Lavandero, S.
Michel, J-B.
Oliveri, C.
Ocaranza Jeraldino, María Paz
Institución
Resumen
Neutral endopeptidase (NEP) hydrolyses angiotensins (Ang) I and II and generates angiotensin-(1-7) [Ang-(17)]. In humans, the insertion/deletion (I/D) angiotensin- I converting enzyme ( ACE) gene polymorphism determined plasma ACE levels by 40%. In rats,