Otro

The genome sequence of the plant pathogen Xylella fastidiosa: The Xylella fastidiosa consortium of the organization for nucleotide sequencing and analysis, Sao Paulo, Brazil

Registro en:
Nature, v. 406, n. 6792, p. 151-157, 2000.
0028-0836
10.1038/35018003
WOS:000088221100037
2-s2.0-0034644159
Autor
Simpson, A. J G
Reinach, F. C.
Arruda, P.
Abreu, F. A.
Acencio, M.
Alvarenga, R.
Alves, L. M C
Araya, J. E.
Baia, G. S.
Baptista, C. S.
Barros, M. H.
Bonaccorsi, E. D.
Bordin, S.
Bové, J. M.
Briones, M. R S
Bueno, M. R P
Camargo, A. A.
Camargo, L. E A
Carraro, D. M.
Carrer, H.
Colauto, N. B.
Colombo, C.
Costa, F. F.
Costa, M. C R
Costa-Neto, C. M.
Coutinho, L. L.
Cristofani, M.
Dias-Neto, E.
Docena, C.
El-Dorry, H.
Facincani, A. P.
Ferreira, A. J S
Ferreira, V. C A
Ferro, J. A.
Fraga, J. S.
França, S. C.
Franco, M. C.
Frohme, M.
Furlan, L. R.
Garnier, M.
Goldman, G. H.
Goldman, M. H S
Gomes, S. L.
Gruber, A.
Ho, P. L.
Hoheisel, J. D.
Junqueira, M. L.
Kemper, E. L.
Kitajima, J. P.
Krieger, J. E.
Kuramae, E. E.
Laigret, F.
Lambais, M. R.
Leite, L. C C
Lemos, E. G M
Lemos, M. V F
Lopes, S. A.
Lopes, C. R.
Machado, J. A.
Machado, M. A.
Madeira, A. M B N
Madeira, H. M F
Marino, C. L.
Marques, M. V.
Martins, E. A L
Martins, E. M F
Matsukuma, A. Y.
Menck, C. F M
Miracca, E. C.
Miyaki, C. Y.
Monteiro-Vitorello, C. B.
Moon, D. H.
Nagai, M. A.
Nascimento, A. L T O
Netto, L. E S
Nhani, A.
Nobrega, F. G.
Nunes, L. R.
Oliveira, M. A.
de Oliveira, M. C.
de Oliveira, R. C.
Palmieri, D. A.
Paris, A.
Peixoto, B. R.
Pereira, G. A G
Pereira, H. A.
Pesquero, J. B.
Quaggio, R. B.
Roberto, P. G.
Rodrigues, V.
Rosa, A. J M
de Rosa, V. E.
de Sá, R. G.
Santelli, R. V.
Sawasaki, H. E.
da Silva, A. C R
da Silva, A. M.
da Silva, F. R.
Silva, W. A.
da Silveira, J. F.
Silvestri, M. L Z
Siqueira, W. J.
de Souza, A. A.
de Souza, A. P.
Terenzi, M. F.
Truffi, D.
Tsai, S. M.
Tsuhako, M. H.
Vallada, H.
Van Sluys, M. A.
Verjovski-Almeida, S.
Vettore, A. L.
Zago, M. A.
Zatz, M.
Meidanis, J.
Setubal, J. C.
Institución
Resumen
Xylella fastidiosa is a fastidious, xylem-limited bacterium that causes a range of economically important plant diseases. Here we report the complete genome sequence of X. fastidiosa clone 9a5c, which causes citrus variegated chlorosis - a serious disease of orange trees. The genome comprises a 52.7% GC-rich 2,679,305-base-pair (bp) circular chromosome and 'two plasmids of 51,158 bp and 1,285 bp. We can assign putative functions to47% of the 2,904 predicted coding regions. Efficient metabolic functions are predicted, with sugars as the principal energy and carbon source, supporting existence in the nutrient-poor xylem sap. The mechanisms associated with pathogenicity and virulence involve toxins, antibiotics and ion sequestration systems, as well as bacterium-bacterium and bacterium-host interactions mediated by a range of proteins. Orthologues of some of these proteins have only been identified in animal and human pathogens; their presence in X. fastidiosa indicates that the molecular basis for bacterial pathogenicity is both conserved and independent of host. At least 83 genes are bacteriophage-derived and include virulence-associated genes from other bacteria, providing direct evidence of phage-mediated horizontal gene transfer.
Materias

Mostrar el registro completo del ítem