Lipid peroxidation: the role or Ca2+ and protection by calcinine

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorPereira, R. S.
dc.date2014-05-27T11:18:06Z
dc.date2016-10-25T21:21:14Z
dc.date2014-05-27T11:18:06Z
dc.date2016-10-25T21:21:14Z
dc.date1996-08-07
dc.date.accessioned2017-04-06T09:22:14Z
dc.date.available2017-04-06T09:22:14Z
dc.identifierEuropean Journal of Drug Metabolism and Pharmacokinetics, v. 21, n. 1, p. 23-26, 1996.
dc.identifier0378-7966
dc.identifierhttp://hdl.handle.net/11449/130470
dc.identifierhttp://acervodigital.unesp.br/handle/11449/130470
dc.identifier10.1007/BF03190274
dc.identifierWOS:A1996UY20800005
dc.identifier2-s2.0-0030035915
dc.identifierhttp://dx.doi.org/10.1007/BF03190274
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/941013
dc.descriptionWhen calcinine (A-23187) (2 mu M), a known Ca2+ ionophore, is present, a significant protection is observed to a mitochondrial suspension undergoing lipid peroxidation by Fe2+-citrate complex. A-23187 can remove Ca2+, which seems to have an important role in the lipid peroxidation process, from its 'lesive sites' and consequently preventing the damage. This information has importance in terms of knowing the mechanisms and avoiding the damages of lipid peroxidation that occur in some pathological cases such as tumor promotion and hemochromatosis.
dc.languageeng
dc.publisherMedecine Et Hygiene
dc.relationEuropean Journal of Drug Metabolism and Pharmacokinetics
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectA-23187
dc.subjectCa2+
dc.subjectLipid peroxidation
dc.subjectMitochondria
dc.subjectCalcimycin
dc.subjectCalcium ion
dc.subjectFerric citrate
dc.subjectAnimal tissue
dc.subjectControlled study
dc.subjectHemochromatosis
dc.subjectLipid peroxidation
dc.subjectMitochondrion
dc.subjectNonhuman
dc.subjectRat
dc.subjectTumor promotion
dc.subjectAnimals
dc.subjectCalcimycin
dc.subjectCalcium
dc.subjectIonophores
dc.subjectLipid Peroxidation
dc.subjectMembrane Potentials
dc.subjectMitochondria, Liver
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectReactive Oxygen Species
dc.titleLipid peroxidation: the role or Ca2+ and protection by calcinine
dc.typeOtro


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