Assessment of structural cardiac abnormalities and diastolic function in women with gestational diabetes mellitus

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorOliveira, Alexandra P.
dc.creatorCalderon, Iracema M. P.
dc.creatorCosta, Roberto A. A.
dc.creatorRoscani, Meliza G.
dc.creatorMagalhães, Claudia G.
dc.creatorBorges, Vera T. M.
dc.date2015-10-21T13:09:09Z
dc.date2016-10-25T20:59:23Z
dc.date2015-10-21T13:09:09Z
dc.date2016-10-25T20:59:23Z
dc.date2015-05-01
dc.date.accessioned2017-04-06T08:57:30Z
dc.date.available2017-04-06T08:57:30Z
dc.identifierDiabetes &vascular Disease Research. London: Sage Publications Ltd, v. 12, n. 3, p. 175-180, 2015.
dc.identifier1479-1641
dc.identifierhttp://hdl.handle.net/11449/128345
dc.identifierhttp://acervodigital.unesp.br/handle/11449/128345
dc.identifierhttp://dx.doi.org/10.1177/1479164114563302
dc.identifierWOS:000352649600003
dc.identifierhttp://dvr.sagepub.com/content/12/3/175
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/938901
dc.descriptionBackground: The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes mellitus, one of the first signs of future cardiovascular disease.Methods: A total of 21 women with gestational diabetes mellitus and 23 healthy pregnant women (control group) between 34 and 37weeks of gestation underwent echocardiographic assessment. The diagnosis of gestational diabetes mellitus was made in agreement with the American Diabetes Association criteria. Echocardiographic images obtained were analysed according to the criteria of the American Society of Echocardiography. Data were analysed using Pearson correlation coefficient, analysis of variance and Student's t-test.Results: Women with gestational diabetes mellitus had higher posterior wall and interventricular septum thickness, increased left ventricular mass and left ventricular mass index, lower early diastolic annular velocity and early diastolic annular velocity/late diastolic annular velocity ratio. There was a positive correlation between left ventricular mass index and fasting glucose and pregnancy body mass index.Conclusion: Patients with gestational diabetes mellitus seem to have a different diastolic profile as well as a mildly dysfunctional pattern on echocardiogram, which may show a need for greater glycaemic control.
dc.languageeng
dc.publisherSage Publications Ltd
dc.relationDiabetes &vascular Disease Research
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDiabetes
dc.subjectPregnancy
dc.subjectCardiac abnormalities
dc.subjectDiastolic function
dc.subjectEchocardiogram
dc.titleAssessment of structural cardiac abnormalities and diastolic function in women with gestational diabetes mellitus
dc.typeOtro


Este ítem pertenece a la siguiente institución