Otro
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
Registro en:
Journal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 22, n. 6, p. 554-559, 2014.
1678-7757
10.1590/1678-775720140209
S1678-77572014000600554
S1678-77572014000600554.pdf
Autor
Mestieri, Leticia Boldrin
Tanomaru-Filho, Mário
Gomes-cornélio, Ana Livia
Salles, Loise Pedrosa
Bernardi, Maria Inês Basso
Guerreiro-Tanomaru, Juliane Maria
Resumen
ObjectiveMineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and MethodFor the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. ResultThe results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. ConclusionIt was concluded that the combination of PC+NbO is a potential alternative for composition of MTA. Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)