Effect of Er,Cr:YSGG laser application in the treatment of experimental periodontitis

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorPavone, Chaine
dc.creatorPerussi, Livia Rodrigues
dc.creatorOliveira, Guilherme José Pimentel Lopes
dc.creatorScardueli, Cássio Rocha
dc.creatorCirelli, Joni Augusto
dc.creatorCerri, Paulo Sérgio
dc.creatorMarcantonio Junior, Elcio
dc.creatorSpolidorio, Luis Carlos
dc.creatorMarcantonio, Rosemary Adriana Chiérici
dc.date2015-08-06T16:12:36Z
dc.date2016-10-25T20:53:17Z
dc.date2015-08-06T16:12:36Z
dc.date2016-10-25T20:53:17Z
dc.date2014
dc.date.accessioned2017-04-06T08:34:57Z
dc.date.available2017-04-06T08:34:57Z
dc.identifierLasers in Medical Science, v. 30, n 3, p. 993-999, 2014.
dc.identifier0268-8921
dc.identifierhttp://hdl.handle.net/11449/125612
dc.identifierhttp://acervodigital.unesp.br/handle/11449/125612
dc.identifierhttp://dx.doi.org/10.1007/s10103-014-1526-3
dc.identifier2628593693450121
dc.identifier3534044399884035
dc.identifierhttp://link.springer.com/article/10.1007%2Fs10103-014-1526-3
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/936208
dc.descriptionThe purpose of this study was to evaluate the influence of an erbium, chromium:yttrium–scandium–gallium–garnet (Er,Cr:YSGG) laser in the absence or presence of manual scaling and root planning (SRP) for the treatment of induced periodontitis in rats. Ligatures were placed in the subgingival region of the maxillary first molar. After a 7-day period, the ligatures were removed, and 40 rats were randomly divided into four groups (G), as follows: (GI) no treatment, (GII) scaling and root planning (SRP) with curettes, (GIII) Er,Cr:YSGG laser irradiation and (GIV) SRP with curettes followed by Er,Cr:YSGG laser irradiation. Seven and 30 days after the treatment, the animals were sacrificed and histologic, histometric and immunohistochemistry analyses were performed. All groups showed similar histopathological characteristics during the evaluation period. The histometric analysis was confirmed using Bonferroni and paired t tests. At 7 and 30 days, groups II, III and IV exhibited greater bone formation in the furcation area when compared to group I (p < 0.0001; p < 0.05). During the 7-day period, the groups irradiated with the laser (III and IV) showed a statistically larger new bone area than the group treated with SRP (II) (p < 0.01). Immunohistochemistry analysis revealed that the control group exhibited a higher expression of tartrate-resistant acid phosphatase (TRAP) and the receptor activator of nuclear factor κΒ ligand (RANKL) when compared to groups II, III and IV (p < 0.05). All treatments were able to reduce the inflammatory processes, consequently enabling the repair of periodontal tissues. The results achieved with the application of the Er,Cr:YSGG laser suggest that this laser can stimulate greater bone formation, especially over a shorter period of time.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.relationLasers in Medical Science
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPeriodontitis
dc.subjectLasers
dc.subjectBone tissue
dc.subjectImmunohistochemistry
dc.subjectHistology
dc.titleEffect of Er,Cr:YSGG laser application in the treatment of experimental periodontitis
dc.typeOtro


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