info:eu-repo/semantics/article
Emerging and reemerging arboviruses: A new threat in Eastern Peru
Fecha
2017-11-14Registro en:
Emerging and reemerging arboviruses: A new threat in Eastern Peru 2017, 12 (11):e0187897 PLOS ONE
1932-6203
10.1371/journal.pone.0187897
PLOS ONE
Autor
Alva-Urcia, Carlos
Aguilar-Luis, Miguel Angel
Palomares-Reyes, Carlos
Silva-Caso, Wilmer
Suárez Ognio, Luis
Weilg, Pablo
Manrique, Carlos
Vasquez-Achaya, Fernando
del Valle, Luis J.
del Valle-Mendoza, Juana
Institución
Resumen
Background Arboviral diseases are one of the most common causes of acute febrile illness (AFI) and a significant health problem in South America. In Peru, laboratory etiologic identification of these infections occurs in less than 50% of cases, leading to underdiagnoses of important emerging arboviruses. Aim To assess the prevalence of the Dengue (DENV), Oropouche (OROV), Chikungunya (CHIKV), Mayaro (MAYV) and Zika (ZIKV) viruses in patients with acute febrile illness from Puerto Maldonado (Peru). Methodology Serum samples were obtained from patients with AFI during January 2016 to March 2016. A total of 139 specimens were analyzed for the presence of DENV, OROV, CHIKV, MAYV, and ZIKV using polymerase chain reaction (PCR). Results CHIKV in 9.4% and OROV in 8.6% were the most prevalent arboviruses, followed by DENV and ZIKV, with a prevalence of 6.5% and 5%, respectively. Among all patients, the most common symptoms accompanying fever were headaches 79.9%, muscle pain 65.5% and joint pain 63.3%. Conclusions During this short 3-month period, 4 arboviruses were detected by PCR, CHIKV and OROV being the most common arboviruses in Puerto Maldonado (Peru). Thus, it is crucial to include OROV detection in the national health surveillance. Furthermore, the etiologic clinical diagnosis of arboviral infections is not possible due to the low specificity of symptoms; therefore an increase of cases confirmed by molecular diagnostic methods will enhance arboviral surveillance in Peru.