Otro
Chromium carbochelate dietary supplementation favored the glucocorticoid response during acute inflammation of Piaractus mesopotamicus
Registro en:
Aquaculture. Amsterdam: Elsevier Science Bv, v. 432, p. 114-118, 2014.
0044-8486
10.1016/j.aquaculture.2014.04.036
WOS:000342247200015
Autor
Castro, Marcello Pardi de
Claudiano, Gustavo Silva
Bortoluzzi, Neida Lucas
Garrido, Eduardo
Fujimoto, Rodrigo Yudi
Andrade Belo, Marco Antonio
Shimada, Marina Tie
Engracia Moraes, Julieta Rodini
Moraes, Flavio Ruas
Resumen
This study was performed to investigate the effect of food supplementation with chromium carbochelate on cortisolemia, glycemia and unspecific acute inflammation of pacus (Piaractus mesopotamicus) challenged by inactivated Aeromonas hydrophila in the swim bladder. 120 pacus (80.5 +/- 11.3 g) were randomly distributed into 24 tanks (310 L, n = 5). After the adaptation period, the pacus were fed diets supplemented with 0 (control), 12, 18 and 36 mg of chromium carbochelate/kg of dry diet for 90 days (ad libitum). Fish fed diets containing 18 and 36 mg of Cr.kg(-1) resulted in a reduction of cortisolemia and glycemia, and in an increase in the inflammatory response, seen through the greater accumulation of lymphocytes and thrombocytes. These results together suggest that food supplementation with chromium carbochelate, at the concentrations of 18 and 36 mg.kg(-1) of feeds, brought homeostatic benefits to P. mesopotamicus. These benefits were translated, at least partially, as reductions in the consequences from inflammatory stress, with diminished cortisolemia and glycemia, which favored accumulation of lymphocytes and thrombocytes at the affected focus, as an increase in the immune response. (C) 2014 Elsevier B.V. All rights reserved. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)