artículo
Studies on quinones. Part 32. Regioselective synthesis of benz[b]phenantridines related to phenantroviridone
Fecha
1999Registro en:
10.1016/S0040-4020(99)00278-1
0040-4020
WOS:000080024200007
Autor
Valderrama, JA
Gonzalez, MF
Valderrama, C
Institución
Resumen
The Diels-Alder reaction of juglone (4) and bromojuglone 18 with 1-cyclohesenecarbosaldehyde dimethylhydrazone (3) is described. Through these cycloaddition reactions 8-hydroxy-1,2,3,4-tetrahydrobenz[b]phenantridin-7,12-dione (5) was obtained in 55 and 78% yield, respectively. Oxidation of 5 to 8-hydroxybenz[b]phenantridin-7,12-dione (6) and 8-hydroxy-1,2,3,4-tetrahydrobenz[b]phenantridin-1,7,12-trione (15) is also reported. (C) 1999 Elsevier Science Ltd. All rights reserved.