artículo
Solubility of boldo leaf antioxidant components (Boldine) in high-pressure carbon dioxide
Fecha
2005Registro en:
10.1016/j.fluid.2005.04.024
1879-0224
0378-3812
WOS:000231625300008
Autor
de la Fuente, JC
Quezada, N
del Valle, JM
Institución
Resumen
This work contributes to the development of an enrichment process for antioxidant compounds in aqueous alcoholic extracts of boldo (Peumus boldus M.) leaves by using high-pressure CO2 as the solvent. Specifically we measured the high-pressure solubility (y(2), molar fraction) of a selected bioactive compound in boldo leaves (boldine) in CO, as a function of system temperature (298 K <= T <= 333 K) and pressure (8 MPa <= P <= 40 MPa). Experimental data was correlated by using a density-based model which is valid for solvent densities > 607 kg/m(3). Predicted solubility values are low (4 x 10(-7) <= y(2) <= 6 x 10(-5)) but comparable with those of nitrogen-containing organic compounds with similar molecular weight (327.4 Da) and solubility parameter (28.3 MPa (0.5) at 313 K) as boldine. (c) 2005 Elsevier B.V. All rights reserved.