Artículo
New Insights and Potential Therapeutic Interventions in Metabolic Diseases
Fecha
2023-07Registro en:
International Journal of Molecular Sciences Open Access Volume 24, Issue 13 July 2023 Article number 10672
16616596
10.3390/ijms241310672
Autor
Clemente-Suárez, Vicente Javier
Martín-Rodríguez, Alexandra
Redondo-Flórez, Laura
López-Mora, Clara
Yáñez-Sepúlveda, Rodrigo
Tornero-Aguilera, José Francisco
Institución
Resumen
Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made.