Otro
Bacterial Cellulose/Chondroitin Sulfate for Dental Materials Scaffolds
Registro en:
Journal Of Biomaterials And Tissue Engineering. Valencia: Amer Scientific Publishers, v. 4, n. 2, p. 150-154, 2014.
2157-9083
10.1166/jbt.2014.1155
WOS:000332917200009
Autor
Olyveira, Gabriel Molina de
Santos, Marcio Luiz dos
Daltro, Paula Braga
Basmaji, Pierre
Daltro, Gildasio de Cerqueira
Guastaldi, Antonio Carlos
Resumen
Bacterial cellulose (BC) has become established as a remarkably versatile biomaterial and can be used in a wide variety of scientific applications, especially for medical devices. In this work, the bacterial cellulose fermentation process is modified by the addition of chondroitin sulfate (1% w/w) to the culture medium before the bacteria are inoculated. Besides, biomimetic precipitation of calcium phosphate of biological interest from simulated body fluid on bacterial cellulose was studied. Chondroitin sulfate influences in bacterial cellulose were analyzed using transmission infrared spectroscopy (FTIR), XRD (X-ray diffraction) and scanning electron microscopy (SEM). FTIR analysis showed interaction between chondroitin sulfate, bacterial cellulose and calcium phosphate and XRD demonstrated amorphous calcium phosphate and carbonated apatite on bacterial cellulose nanocomposites. SEM images confirmed incorporation of calcium phosphate in bacterial celluloe nanocomposite surface and uniform spherical calcium phosphate particles. Future experiments with cells adhesion and viability are in course.