Complete mitochondrial genome sequence of the eastern gorilla (Gorilla beringei) and implications for African ape biogeography

dc.creatorSoto Calderón, Iván Darío
dc.creatorDas, Ranajit
dc.creatorHergenrother, Scott D.
dc.creatorDew, J. Larry
dc.creatorAnthony, Nicola
dc.creatorJensen Seaman, Michael
dc.date2023-04-07T01:10:08Z
dc.date2023-04-07T01:10:08Z
dc.date2014
dc.date.accessioned2024-04-23T18:10:48Z
dc.date.available2024-04-23T18:10:48Z
dc.identifierDas R, Hergenrother SD, Soto-Calderón ID, Dew JL, Anthony NM, Jensen-Seaman MI. Complete mitochondrial genome sequence of the Eastern gorilla (Gorilla beringei) and implications for african ape biogeography. J Hered. 2014 Nov-Dec;105(6):752-61. doi: 10.1093/jhered/esu056.
dc.identifier0022-1503
dc.identifierhttps://hdl.handle.net/10495/34490
dc.identifier10.1093/jhered/esu056
dc.identifier1465-7333
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9230485
dc.descriptionABSTRACT: The Western and Eastern species of gorillas (Gorilla gorilla and Gorilla beringei) began diverging in the mid-Pleistocene, but in a complex pattern with ongoing gene flow following their initial split. We sequenced the complete mitochondrial genomes of 1 Eastern and 1 Western gorilla to provide the most accurate date for their mitochondrial divergence, and to analyze patterns of nucleotide substitutions. The most recent common ancestor of these genomes existed about 1.9 million years ago, slightly more recent than that of chimpanzee and bonobo. We in turn use this date as a calibration to reanalyze sequences from the Eastern lowland and mountain gorilla subspecies to estimate their mitochondrial divergence at approximately 380 000 years ago. These dates help frame a hypothesis whereby populations became isolated nearly 2 million years ago with restricted maternal gene flow, followed by ongoing male migration until the recent past. This process of divergence with prolonged hybridization occurred against the backdrop of the African Pleistocene, characterized by intense fluctuations in temperature and aridity, while at the same time experiencing tectonic uplifting and consequent shifts in the drainage of major river systems. Interestingly, this same pattern of introgression following divergence and discrepancies between mitochondrial and nuclear loci is seen in fossil hominins from Eurasia, suggesting that such processes may be common in hominids and that living gorillas may provide a useful model for understanding isolation and migration in our extinct relatives.
dc.descriptionCOL0006723
dc.format10
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherOxford University Press For The American Genetic Association
dc.publisherGenética Molecular (GENMOL)
dc.publisherNueva York, Estados Unidos
dc.relationJ. Hered.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectHominidae
dc.subjectGenome, Mitochondrial
dc.subjectGenoma Mitocondrial
dc.subjectPrimates
dc.subjectHaplotypes
dc.subjectHaplotipos
dc.subjectBayes Theorem
dc.subjectTeorema de Bayes
dc.subjectBiological Evolution
dc.subjectEvolución Biológica
dc.subjectGenetic Variation
dc.subjectVariación Genética
dc.subjectGorilla gorilla
dc.subjectFilogenia
dc.subjectPhylogeny
dc.subjectSequence Analysis, DNA
dc.subjectAnálisis de Secuencia de ADN
dc.titleComplete mitochondrial genome sequence of the eastern gorilla (Gorilla beringei) and implications for African ape biogeography
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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