Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesis

Rodríguez Osorio, Nélida; Uzun, Alper; Kaya, Abdullah; Wang, Hongfeng; Parrish, John J.; Ilyin, Valentin A.; Memili, Erdogan

info:eu-repo/semantics/article

Registro en:

Uzun A, Rodríguez-Osorio N, Kaya A, Wang H, Parrish JJ, Ilyin VA, Memili E. Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesis. BMC Genomics. 2009 Apr 24;10:183. doi: 10.1186/1471-2164-10-183.

https://hdl.handle.net/10495/33392

10.1186/1471-2164-10-183

1471-2164

https://repositorioslatinoamericanos.uchile.cl/handle/2250/9230273

Autor

Rodríguez Osorio, Nélida

Uzun, Alper

Kaya, Abdullah

Wang, Hongfeng

Parrish, John J.

Ilyin, Valentin A.

Memili, Erdogan

Institución

Universidad de Antioquia (Colombia)

Resumen

ABSTRACT: Background: Embryonic genome activation (EGA) is a critical event for the preimplantation embryo, which is manifested by changes in chromatin structure, transcriptional machinery, expression of embryonic genes, and degradation of maternal transcripts. The objectives of this study were to determine transcript abundance of HMGN3a and SMARCAL1 in mature bovine oocytes and early bovine embryos, to perform comparative functional genomics analysis of these genes across mammals.

COL0001262

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