info:eu-repo/semantics/conferenceObject
Nanoformulation prototype based on a natural extract for the potential treatment of type 2 diabetes mellitus
Autor
Escobar Chaves, Elkin Leandro
Acín Martínez, Sergio
Fernández Culma, Maritza
Muñoz, Diana Lorena
Echeverri, Alexandra
Echeverri López, Luis Fernando
Orozco Holguín, Jahir
Balcázar Morales, Norman
Institución
Resumen
ABSTRACT: Triterpene-enriched fractions (OBE100) from Eucalyptus tereticornis
demonstrated efficiency when administered intraperitoneally to diet-induced
obesity (DIO) mouse model to treat obesity-related type 2 diabetes mellitus
(T2DM)1; however, its oral administration has not yet led to satisfactory
results. We aimed to develop an oral nano formulation that enhanced the
promising effect of the OBE 100 fraction, guaranteeing higher stability and
bioavailability of the pharmacologically active components present in the
natural extract through the oral route. COL0006723 COL0015339 COL0202529