Different legal frameworks and concepts have been used to establish coastal zone boundaries. Integrated Coastal Zone Management use some criteria, while Land-Use Planning use a different criteria. A critical analysis about this topic is done in the present study, with the aim of proposing a novel method for delimitation and demarcation of coastal zone boundaries. The method offers an integrated perspective regarding the river basin, the coastal zone, and their corresponding economic zones. Moreover, it is comprised of dependent and independent variables, representing useful decision-making tools for applying Integrated Coastal Zone Management and Land-Use Planning initiatives. The concepts of Primary Environmental Coastal Units for Integrated Management (PECUIM) and Basic Environmental Coastal Units for Integrated Management and Land-Use Planning (BECUIMLUP) were proposed and applied in Cuba, where twenty-three PECUIM and four BECUIMLUP were demarcated and delimitated. At the end of this paper, the importance of integrated criteria for coastal zone boundaries is concluded and demonstrated.