The emergence of a novel coronavirus (SARS-CoV-2), their biology and therapeutic options

dc.creatorKhan, Suliman
dc.creatorSiddique, Rabeea
dc.creatorShereen, Muhammad Adnan
dc.creatorAli, Ashaq
dc.creatorLiu, Jianbo
dc.creatorBai, Qian
dc.creatorBashir, Nadia
dc.date2020-03-30T18:43:27Z
dc.date2020-03-30T18:43:27Z
dc.date2020-03
dc.date.accessioned2023-09-28T20:08:31Z
dc.date.available2023-09-28T20:08:31Z
dc.identifierKHAN, S. et al. The emergence of a novel coronavirus (SARS-CoV-2), their biology and therapeutic options. Journal of Clinical Microbiology, [S.l.], Mar. 2020.
dc.identifierhttps://jcm.asm.org/content/early/2020/03/05/JCM.00187-20
dc.identifierhttp://repositorio.ufla.br/jspui/handle/1/39558
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9045459
dc.descriptionThe new decade of the 21st century (2020) started with the emergence of novel coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease (COVID-19) in Wuhan, China. It is the third highly pathogenic and transmissible coronavirus after severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in humans. The source of origin, transmission to humans and mechanisms associated with the pathogenicity of SARS-CoV-2 are not clear yet, however, its resemblance with SARS-CoV and several other bat coronaviruses was recently confirmed through genome sequencing related studies. The development of therapeutic strategies is necessary in order to prevent further epidemics and cure infected people. In this Review, we summarize current information about the emergence, origin, diversity, and epidemiology of three pathogenic coronaviruses with a specific focus on the current outbreak in Wuhan, China. Furthermore, we discuss the clinical features and potential therapeutic options that may be effective against SARS-CoV-2.
dc.languageen_US
dc.publisherAmerican Society for Microbiology
dc.rightsrestrictAccess
dc.sourceJournal of Clinical Microbiology
dc.subjectNovel coronavirus - Outbreak
dc.subjectNovel coronavirus - Therapeutics
dc.titleThe emergence of a novel coronavirus (SARS-CoV-2), their biology and therapeutic options
dc.typeArtigo


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