Artigo
Unusual 2(1H)-Pyrazinones isolated from a culture of a brazilian marine-derived Streptomyces sp.
Registro en:
THOMASI, S. S. et al. Unusual 2(1H)-Pyrazinones isolated from a culture of a brazilian marine-derived Streptomyces sp. Natural Product Communications, [S.l.], v. 9, n. 9, p. 1275-1278, April 2015.
Autor
Thomasi, Sérgio S.
Granato, Ana C.
Romano, Luis H.
Dhooghe, Liene
Nascimento, Eduardo S. P. do
Badino, Alberto C.
Silva, Maria F. G. F. da
Ferreira, Antonio G.
Venâncio, Tiago
Institución
Resumen
Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain
designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and
HRMS. The application of this system to identify, purify and elucidate all the structures is described.