Artigo de Periódico
Production of L-asparaginase by filamentous fungi
Registro en:
0074-0276
1678-8060
Autor
SARQUIS, Maria Inez de Moura
OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
Institución
Resumen
L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.