A New Prenylisoflavone from the Antifungal Extract of Leaves of Vatairea guianensis Aubl.

dc.creatorSOUZA, Ronilson Freitas de
dc.creatorSILVA, Geilson Alcantara da
dc.creatorARRUDA, Alberto Cardoso
dc.creatorSILVA, Milton Nascimento da
dc.creatorSANTOS, Alberdan Silva
dc.creatorGRISÓLIA, Daniella Paternostro de Araújo
dc.creatorSILVA, Moisés Batista da
dc.creatorARRUDA, Mara Silvia Pinheiro
dc.date2017-07-18T20:08:52Z
dc.date2017-07-18T20:08:52Z
dc.date2017-06
dc.date.accessioned2023-09-28T15:38:16Z
dc.date.available2023-09-28T15:38:16Z
dc.identifierSOUZA, Ronilson Freitas de et al. A New Prenylisoflavone from the Antifungal Extract of Leaves of Vatairea guianensis Aubl. Journal of the Brazilian Chemical Society, São Paulo, v. 28, n. 6, p. 1132-1136, jun. 2017. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000601132&lng=pt&nrm=iso>. Acesso em: 18 jul. 2017. <http://dx.doi.org/10.21577/0103-5053.20160250>.
dc.identifier1678-4790
dc.identifierhttp://repositorio.ufpa.br/jspui/handle/2011/8875
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9018302
dc.descriptionA new compound, 5,7,3'-trihydroxy-4'-methoxy-8-prenylisoflavone, was isolated from the leaves of Vatairea guianensis Aubl. (Fabaceae), together with two known isoflavones lupiwighteone and 5,7,4'-trihydroxy-3'-methoxy-8-prenylisoflavone. All isolated compounds were characterized based on infrared (IR), UV, 1H and 13C nuclear magnetic resonance (NMR), including 2D NMR analyses and high resolution mass spectrometry. The ethanolic extract from V. guianensis leaves displayed activity against Candida dubliniensis, C. albicans and C. krusei. However, the EtOAc fraction from that extract exhibited more significant activity than the ethanolic extract, showing antifungal activity for all fungi species investigated. The major compound 5,7,3'-trihydroxy-4'-methoxy-8-prenylisoflavone isolated from that EtOAc fraction was also active against C. parapsilosis and C. dubliniensis.
dc.formatapplication/pdf
dc.languagepor
dc.publisherUniversidade Federal do Pará
dc.publisherBrasil
dc.publisherUFPA
dc.relationJournal of the Brazilian Chemical Society
dc.rightsAcesso Aberto
dc.subjectAntifúngicos
dc.subjectVatairea guianensis
dc.subjectFlavonóides
dc.subjectFabaceae
dc.subjectPrenilisoflavona
dc.titleA New Prenylisoflavone from the Antifungal Extract of Leaves of Vatairea guianensis Aubl.
dc.typeArtigo de Periódico


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