A versatile physical phantom design and construction for I-125 dose measurements and dose-to-medium determination

dc.creatorANTUNES, PAULA C.G.
dc.creatorSIQUEIRA, PAULO de T.D.
dc.creatorSHORTO, JULIAN M.B.
dc.creatorYORIYAZ, HELIO
dc.date2023
dc.date2023-04-26T14:13:36Z
dc.date2023-04-26T14:13:36Z
dc.date.accessioned2023-09-28T14:25:50Z
dc.date.available2023-09-28T14:25:50Z
dc.identifier1538-4721
dc.identifierhttp://repositorio.ipen.br/handle/123456789/34007
dc.identifier1
dc.identifier22
dc.identifier10.1016/j.brachy.2022.10.005
dc.identifier0000-0003-4023-236X
dc.identifier0000-0003-4817-5275
dc.identifier0000-0003-2281-5756
dc.identifier18.9
dc.identifier48
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9004216
dc.descriptionPURPOSE: In this paper we present a phantom designed to provide conditions to generate set of ???true??? independent reference data as requested by TG-186, and mitigating the scarcity of experimental studies on brachytherapy validation. It was used to perform accurate experimental measurements of dose of 125I brachytherapy seeds using LiF dosimeters, with the objective of experimentally validating Monte Carlo (MC) calculations with model-based dose calculation algorithm (MBDCA). In addition, this work intends to evaluate a methodology to convert the experimental values from LiF into dose in the medium. METHODS AND MATERIALS: The proposed PMMA physical phantom features cavities to insert a LiF dosimeter and a 125I seed, adjusted in different configurations with variable thickness. Monte Carlo calculations performed with MCNP6.2 code were used to score the absorbed dose in the LiF and the dose conversion parameters. A sensitivity analysis was done to verify the source of possible uncertainties and quantify their impact on the results. RESULTS: The proposed phantom and experimental procedure developed in this work provided precise dose data within 5.68% uncertainty (k???=???1). The achieved precision made it possible to convert the LiF responses into absorbed dose to medium and to validate the dose conversion factor methodology. CONCLUSIONS: The proposed phantom is simple both in design and as in its composition, thus achieving the demanded precision in dose evaluations due to its easy reproducibility of experimental setup. The results derived from the phantom measurements support the dose conversion methodology. The phantom and the experimental procedure developed here can be applied for other materials and radiation sources.
dc.format80-92
dc.relationBrachytherapy
dc.rightsopenAccess
dc.subjectbiological models
dc.subjectphantoms
dc.subjectbrachytherapy
dc.subjectiodine 125
dc.subjectseeds
dc.subjectlithium fluorides
dc.subjectmonte carlo method
dc.titleA versatile physical phantom design and construction for I-125 dose measurements and dose-to-medium determination
dc.typeArtigo de peri??dico
dc.coverageI


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