This study aims at expanding the knowledge on the applicability of bone meal powder (BMP), and assess its potential as an adsorbent material for methylene blue (MB) removal, a toxic textile dye. BMP is a low-cost material still little studied for the adsorption of contaminants in aqueous media. In this work, we employed the 2k experimental design (k = 3) to systematically explore the most important process parameters, which were pH of the MB solution, initial MB concentration in solution and biosorbent dosage (mass of biosorbent/volume of contaminated solutions).