Resumos em peri??dicos
Three-dimensional cellular culture system for testing of biological effects of radiations in tumoral and non-tumoral models
Registro en:
1867-2450
6
13
10.1007/s12551-021-00844-3
0000-0002-0007-534X
Sem Percentil
90.00
Autor
VIEIRA, DANIEL P.
Resumen
In vitro cell cultures are a well-known controlled test system
used to analyze tumor physiologic responses upon negative
stimuli. Updated techniques, us-ing three-dimensional
organization of cells in cultures, are being increasingly used
to this purpose. Research organizations and industry are
striving to pro-duce in vitro tumor surrogates that could be
better test systems to antitumor agents as new compounds or
to study radiation effects on cancers. The presentation will
show some techniques currently used to build and maintain
these specific cell cultures, and how experiments are
evolving towards the production of tumoroids, or tumoral
organoids, which will include various cell types and additive
manufacturing. Funda????o de Amparo ?? Pesquisa do Estado de S??o Paulo (FAPESP) Financiadora de Estudos e Projetos (FINEP) FAPESP: 17/50332-0 FINEP: 23784-17